【摘要】 目的 旨在评估快速交换球囊技术应用于Marshall静脉(vein of Marshall, VOM)无水酒精消融术中的安全性与可行性。方法 回顾性分析2024年2月至2024年8月就诊于河南省人民医院首次行射频消融术及VOM无水酒精消融的48例持续性房颤患者的临床资料。依据VOM无水酒精消融过程中球囊封堵方法的差异，将患者分为整体交换(over the wire, OTW)球囊组(26例)与快速交换球囊组(22例)。对比两组患者术中二尖瓣峡部阻断率、二尖瓣峡部总消融时间、球囊封堵时间、总手术时间、X线透视时间以及手术相关并发症的发生情况。结果 两组患者的二尖瓣峡部阻断率、二尖瓣峡部总消融时间以及总手术时间比较差异无统计学意义(P>0.05)。相比于OTW球囊组，快速交换球囊组的球囊封堵时间减少[10.00(9.00,12.25) min vs 11.50(10.00,15.00) min,Z=-2.211,P=0.027]、X线透视时间降低[8.50(7.75,9.25) min vs 9.50(8.00,10.25)min,Z=-2.099,P=0.036]。两组患者术后均未出现严重并发症。结论 快速交换球囊技术应用于VOM无水酒精消融术具备安全性与可行性，值得临床推广应用。更多还原

【Abstract】 Objective To assess the safety and feasibility of the rapid-exchange balloon technique in the ethanol ablation of the vein of Marshall(VOM).Methods The clinical data of 48 patients with persistent atrial fibrillation who underwent radiofrequency ablation and ethanol ablation within the VOM at Henan Provincial People’s Hospital from February 2024 to August 2024 were retrospectively analyzed.According to the differences in balloon occlusion methods during VOM ethanol ablation, the patients were divided into the over the wire(OTW) balloon group(26 cases) and the rapidexchange balloon group(22 cases).The intraoperative mitral valve isthmus blockade rate, total mitral valve isthmus ablation time, balloon occlusion time, total operation time, X-ray fluoroscopy time, and the incidence of surgery-related complications were compared between the two groups.Results There was no statistically significant difference between the two groups of patients in mitral isthmus blockade rate, the total ablation time of the mitral isthmus, and the total operation time(P>0.05).Compared with the OTW balloon group, the balloon occlusion time was reduced [10.00(9.00,12.25) min vs 11.50(10.00,15.00) min, Z=-2.211,P=0.027] and X-ray fluoroscopy time was decreased [8.50(7.75,9.25) min vs 9.50(8.00,10.25) min, Z=-2.099,P=0.036] in the rapid exchange balloon group.No serious complications occurred in either group.Conclusion The rapid exchange balloon technology is safe and feasible in VOM ethanol ablation, which is worthy of clinical promotion and application.更多还原