【摘要】 长期航天飞行下空间位置的剧变打破了地球固有的昼夜明暗等环境周期性信号，导致外界环境周期与人体的内源性生物节律之间发生错位。这种“时差”效应持续累积，对节律调控的核心生物通路产生严重干扰，引发以睡眠-觉醒障碍为代表的一系列神经内分泌及行为应激反应，已成为制约长期空间任务的成功与航天员健康的核心医学问题。中医学认为顺应天地昼夜四时的节律性变化，维系机体阴阳二气的动态平衡与和谐运转，是保障生命活力、抵御外邪内伤的根本法则。而在长期失重、幽闭、光照异常的深空飞行环境中，人体与自然节律的纽带被强行割裂，阴阳之气难以维系，升降出入之机受阻，脏腑气化功能受损，气血循行乖戾，终致“百病丛生”之虞。本文立足于中医“天人相应”的时间医学观与阴阳气血理论，深入梳理历代典籍与现代研究中应对节律紊乱、调和阴阳的穴位干预经验。在此基础上，创新性地提出并论证一个整合性的穴位处方策略——“背心五穴”协同下肢调节人体昼夜阴阳跷脉动态平衡的经典对穴照海-申脉及引气下行的经典对穴太冲-涌泉。此配伍旨在从“心脑-阴阳-肝肾”多层次入手，使心神得安、脑府得清、肝肾得补，阴阳之气复归有序协调，从而助力紊乱的生物节律系统重获稳态，为保障航天员长期在轨健康提供具有中医特色的“调时复衡”新思路。更多还原

【Abstract】 Long-term spaceflight, characterized by drastic changes in spatial position, disrupts the Earth’s inherent environmental periodic signals, such as the day-night light-dark cycle. This leads to a misalignment between the external environmental cycles and the body’s endogenous biological rhythms. The cumulative effect of this persistent "time difference" severely disrupts the core biological pathways that regulate the circadian rhythm. It triggers a series of neuroendocrine and behavioral stress responses, exemplified by sleep-wake disorders, which have become a core medical problem constraining the success of long-term space missions and astronaut health. Traditional Chinese Medicine(TCM) posits that aligning with the rhythmic changes of heaven, earth, day, night, and the four seasons, and maintaining the dynamic balance and harmonious functioning of the body’s Yin and Yang vital energies, are fundamental principles for safeguarding vitality and resisting external pathogens and internal injuries. However, in the prolonged weightlessness, confinement, and abnormal lighting environment of deep space flight, the bond between the human body and natural rhythms is forcibly severed. Yin and Yang Qi become difficult to sustain, the mechanisms of ascent, descent, exit, and entry are obstructed, the visceral Qi transformation functions are impaired, and the circulation of Qi and Blood becomes disordered, ultimately leading to the onset of various disorders. This paper, grounded in the TCM temporal medicine perspective of "correspondence between heaven and human"(tian ren xiang ying) and the theories of Yin-Yang and Qi-Blood, meticulously reviews the historical classics and modern research on acupoint intervention strategies for addressing rhythm disorders and harmonizing Yin and Yang. Building upon this foundation, it innovatively proposes and argues for an integrated acupoint prescription strategy: the “Bei Xin Wu Xue” combined with the classic paired points Zhaohai(KI6)-Shenmai(BL62) on the lower limbs to regulate the dynamic balance of the Yin and Yang Heel Vessels(Yin/Yang Qiao Mai), and the classic paired points Taichong(LR3)-Yongquan(KI1) to guide Qi downward. This combination aims to work at multiple levels – "Heart-Brain, Yin-Yang, Liver-Kidney" –to calm the Heart Spirit, clear the Brain Mansion, and tonify the Liver and Kidney. The goal is to restore Yin and Yang Qi to an orderly and coordinated state, thereby assisting the disordered biological rhythm system in regaining homeostasis. This provides a novel TCM-inspired approach of "rhythm regulation and equilibrium restoration"(tiao shi fu heng) to safeguard the long-term in-orbit health of astronauts.更多还原