【摘要】 目的：观察益气养阴汤对肺癌根治术后患者肺功能及癌因性疲乏恢复情况的影响。方法：将132例肺癌根治术后患者按照随机数字表法分为对照组62例和观察组70例。对照组给予常规西药治疗联合呼吸功能锻炼，观察组在对照组治疗的基础上联合益气养阴汤。比较两组患者的临床疗效、并发症发生率及治疗前后中医证候积分、肺功能[每分钟最大通气量(maximal voluntary ventilation, MVV)、第一秒用力呼气容积(forced expiratory volume in one second, FEV1)、用力肺活量(forced vital capacity, FVC)]、Piper疲乏量表(Piper fatigue scale, PFS)评分变化情况。结果：观察组有效率为97.14%,对照组有效率为87.10%,观察组高于对照组，差异具有统计学意义(P<0.05)。两组患者治疗后五心烦热、胸痛胸闷、神疲乏力、脉虚无力等中医证候积分低于本组治疗前，且治疗后观察组低于对照组(P<0.05)。两组患者治疗后MVV、FEV1、FVC等肺功能指标较高于本组治疗前，且治疗后观察组高于对照组，差异具有统计学意义(P<0.05)。两组患者治疗后PFS评分低于本组治疗前，且治疗后观察组低于对照组(P<0.05)。两组患者术后并发症发生率比较，差异无统计学意义(P>0.05)。结论：肺癌根治术后运用益气养阴汤进行治疗，能够显著改善患者的中医证候，减轻癌因性疲乏程度，提高肺功能。更多还原

【Abstract】 Objective: To observe the effect of Qi-Tonifying and Yin-Nourishing Decoction on the recovery of pulmonary function and cancer-related fatigue in patients after radical surgery of lung cancer.Methods: A total of 132 patients after radical surgery of lung cancer were randomly divided into the control group with 62 cases and the observation group with 70 cases respectively according to the random number table method.The control group was treated with conventional Western medicine and respiratory function exercises, while the observation group was treated with Qi-Tonifying and Yin-Nourishing Decoction in addition to the treatment of the control group.The clinical efficacy, incidence of complications, changes in TCM syndrome scores, pulmonary function[including maximal voluntary ventilation(MVV),forced expiratory volume in one second(FEV1),forced vital capacity(FVC)],and Piper fatigue scale(PFS) scores before and after treatment were compared between the two groups.Results: The effective rate of the observation group was 97.14%,which was higher than 87.10% of the control group, and the difference was statistically significant(P<0.05).The TCM syndrome scores of both groups after treatment were lower than those before treatment, and the scores of the observation group were lower than those of the control group after treatment(P<0.05).The pulmonary function indicators(such as MVV,FEV1,FVC) of both groups were higher than those before treatment, and the observation group′s above indicators were higher than those of the control group, with statistically significant differences(P<0.05).The PFS scores of both groups were lower than those before treatment, and the observation group′s PFS score was lower than that of the control group(P<0.05).There was no statistically significant difference in the incidence of postoperative complications between the two groups(P>0.05).Conclusion: Qi-Tonifying and Yin-Nourishing Decoction in the treatment of patients after radical surgery of lung cancer can significantly improve TCM syndromes, alleviate the degree of cancer-related fatigue, and enhance pulmonary function.更多还原