【摘要】 针灸技术在现代医疗中的创新需求日益增长，纳米材料因其微小尺度的特殊性能与精准控制能力，为传统针灸的作用原理研究和器械升级打开了跨学科合作的新窗口。本文系统回顾了纳米技术与针灸学交叉领域的最新研究进展。在机制探索方面，纳米传感技术通过实时监测针刺过程中神经递质的动态变化，为经络腧穴的生物信息传导机制提供了分子层面的证据。在医疗应用方面，纳米载药微针系统和智能针灸设备的开发，显著提高了经皮给药效率和生物标志物检测的灵敏度，推动了针灸治疗从经验性操作向精准调控的转变。目前，研究已初步建立起“材料功能化修饰-靶向递送优化-能量精准调控”的技术体系，并在退行性疾病防治和慢性疼痛管理等领域展现出独特的优势。尽管针灸与纳米技术的融合仍处于研究阶段，但其潜在的应用前景令人期待，为传统医学的现代化提供可持续的技术支撑。更多还原

【Abstract】 The demand for innovation in acupuncture technology within modern healthcare is increasing.Nanomaterials, owing to their unique properties at the nanoscale and precise controllability, open new avenues for interdisciplinary collaboration in researching the mechanisms of traditional acupuncture and upgrading its instruments. This article systematically reviews recent advancements at the intersection of nanotechnology and acupuncture research. In mechanistic exploration, nanosensing technologies enable real-time monitoring of dynamic neurotransmitter changes during acupuncture, providing molecular-level evidence for the biological information transmission mechanisms of meridians and acupoints. In medical applications, the development of nano-drug-loaded microneedle systems and intelligent acupuncture devices significantly enhances transdermal drug delivery efficiency and the sensitivity of biomarker detection, promoting the evolution of acupuncture therapy from empirical practice towards precise regulation. Current research has preliminarily established a technical framework encompassing "material functionalization modification-targeted delivery optimization-precise energy regulation", demonstrating unique advantages in areas such as prevention and treatment of degenerative diseases and chronic pain management. Although the integration of acupuncture and nanotechnology is still in the research stage, its potential application prospects are promising, offering sustainable technological support for the modernization of traditional medicine.更多还原