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从虚、瘀、毒论类风湿关节炎的病因病机

Discussion on the Etiology and Pathogenesis of Rheumatoid Arthritis from the Perspective of Deficiency, Stasis and Toxin

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【作者】 叶子丰; 谭旭仪; 邝高艳; 匡建军; 卢敏;

【Author】 YE Zifeng;TANG Xuyi;KUANG Gaoyan;KUANG Jianjun;LU Ming;Hunan University of Chinese Medicine;The Affiliated Hospital of Hunan Academy of Traditional Chinese Medicine;The First Hospital of Hunan University of Chinese Medicine;

【通讯作者】 谭旭仪;

【机构】 湖南中医药大学; 湖南省中医药研究院附属医院; 湖南中医药大学第一附属医院;

【摘要】 根据类风湿关节炎的疾病特点,从虚、瘀、毒探讨类风湿关节炎(RA)的病因病机。虚、瘀、毒与类风湿关节炎病机理论内涵贴合。虚为正气不足,表现为机体免疫调节失衡,导致RA的易感性增加;瘀涉及血液循环障碍,与RA中的炎症和关节损伤密切相关;毒为外来或内生的有害物质,包括自身免疫反应产生的炎症介质,可加剧RA的病理进程。

【Abstract】 Based on the disease characteristics of rheumatoid arthritis(RA), this article discusses the etiology and pathogenesis of RA from the aspects of deficiency, stasis and toxin. Deficiency, stasis and toxin are consistent with the theoretical connotation of RA pathogenesis. Deficiency refers to the insufficiency of vital Qi, manifested as the imbalance of immune regulation, leading to increased susceptibility to RA. Stasis involves blood circulation disorders, which are closely related to inflammation and joint damage in RA. Toxin refers to foreign or endogenous harmful substances, including inflammatory mediators produced by autoimmune reactions, which can aggravate the pathological process of RA.

【关键词】 类风湿关节炎; 虚; 瘀; 毒; 病因病机;
【Key words】 rheumatoid arthritis; deficiency; stasis; toxin; etiology and pathogenesis;
【基金】 国家自然科学基金项目(82174414,82274543);国家中医药管理局全国名老中医药专家传承工作室建设项目(国中医药人教函[2022]75号);湖南省中医药管理局“十四五”第一批中医药领军人才培养项目(rsk-023-01)
  • 【文献出处】 中医药导报 ,Guiding Journal of Traditional Chinese Medicine and Pharmacy , 编辑部邮箱 ,2025年06期
  • 【分类号】R259
  • 【下载频次】72
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