【摘要】 【目的】探讨体成分指标与学龄儿童维生素D水平的相关性。【方法】选择2020年3月至9月在湖南省儿童医院儿童保健所门诊就诊的440例7～12岁学龄儿童，根据维生素D水平情况，将维生素D缺乏及不足的患儿纳入维生素D异常组(n=171),维生素D充足的儿童纳入维生素D正常组(n=269)。应用生物电阻抗法测量体脂肪量(BF)、蛋白质、无机盐、身体总水分、肌肉量(SMM)、内脏脂肪面积(VFA)、腰臀比(WHR)、体脂百分比(BFP)等体成分指标，采用Pearson系数分析体成分指标与血清25-羟基维生素D[25-(OH)D]水平的相关性，采用Logistic回归分析不同体成分指标对维生素D水平的影响。【结果】维生素D正常组儿童的BF、蛋白质、无机盐、身体总水分、SMM、VFA均低于维生素D异常组儿童，差异均有统计学意义(P<0.05)。Pearson相关性分析显示，BF、蛋白质、无机盐、身体总水分、SMM、VFA、WHR、BFP与血清25-(OH)D水平均呈负相关(P<0.05)。多因素Logistic回归分析显示：BF的回归系数值为0.172,OR(95%CI)为1.187(1.004,1.404)(P<0.05);WHR的回归系数值为6.365,OR(95%CI)为581.434(12.150,27 824.271)(P<0.05)。【结论】学龄儿童体成分指标与维生素D水平具有一定的相关性，体成分指标中体BF及WHR是维生素D异常的预测变量。更多还原

【Abstract】 【Objective】 To investigate the correlation between body composition indices and vitamin D levels in school-age children. 【Methods】A total of 440 school-age children aged 7-12 years who visited the outpatient department of Child Health Care in Hunan Children’s Hospital from March to September 2020 were enrolled. According to their vitamin D levels, the children with vitamin D deficiency or insufficiency were assigned to the abnormal vitamin D group(n=171), and those with sufficient vitamin D were assigned to the normal vitamin D group(n=269). Bioelectrical impedance analysis was used to measure body composition indices including body fat mass(BF), protein, mineral salts, total body water, skeletal muscle mass(SMM), visceral fat area(VFA), waist-to-hip ratio(WHR), and body fat percentage(BFP). Pearson correlation coefficient was used to analyze the correlation between body composition indices and serum 25-hydroxyvitamin D [25-(OH)D] levels, and logistic regression analysis was performed to evaluate the effects of different body composition indices on vitamin D nutritional status. 【Results】The levels of BF, protein, mineral salts, total body water, SMM and VFA in the normal vitamin D group were significantly lower than those in the abnormal vitamin D group(P<0.05). Pearson correlation analysis showed that BF, protein, mineral salts, total body water, SMM, VFA, WHR and BFP were all negatively correlated with vitamin D levels, with statistically significant differences(P<0.05). Multivariate logistic regression analysis revealed that the regression coefficient of BF was 0.172, with an odds ratio(OR) of 1.187 [95% confidence interval(CI):1.004, 1.404](P<0.05); the regression coefficient of WHR was 6.365, with an OR of 581.434(95%CI: 12.150, 27 824.271)(P<0.05). 【Conclusion】Body composition indices are correlated with vitamin D levels in school-age children. Among these indices, body fat mass and waist-to-hip ratio are predictive variables for abnormal vitamin D status.更多还原