【摘要】 【目的】探讨儿童胰母细胞瘤的影像学表现与病理特征的相关性，提高对该疾病的诊断准确性。【方法】回顾性分析2015年9月至2024年12月本院收治的经术后病理诊断证实为胰母细胞瘤的9例患儿的临床资料，对其CT、MRI等影像学资料进行详细分析，并与病理结果进行对照分析。【结果】9例患者，3例发生于胰头区，5例发生于胰体区，1例发生于胰体及胰尾。CT表现为混杂密度肿瘤，呈分叶状，9例均可见坏死、钙化，增强扫描动脉期表现为不均匀轻度强化，6例呈渐进性强化；T₁WI呈低信号或等信号，T₂WI呈等信号或高信号，增强后不均匀强化，1例主胰管扩张。影像学图像上表现为边界清晰的肿瘤，病理组织学图像上多可见相对完整的纤维包膜，而边界模糊的肿瘤在病理组织学图像上往往显示肿瘤细胞向周围组织浸润生长，包膜不完整或缺失。影像学图像上肿瘤的强化模式与病理组织学图像上肿瘤的血管分布密切相关。【结论】胰母细胞瘤在不同影像学检查中具有一定特征性表现，且与病理改变密切相关。影像学检查对儿童胰母细胞瘤的诊断、鉴别诊断及术前评估具有重要价值，结合病理特征可进一步提高诊断的准确性，为临床治疗方案的制定提供有力依据。更多还原

【Abstract】 【Objective】To explore the correlation between imaging manifestations and pathological features of pancreatoblastoma in children, and to improve the diagnostic accuracy of this disease.【Methods】 The clinical data of 9 children pathologically confirmed as pancreatoblastoma after surgery were retrospectively analyzed. The CT and MRI imaging data of the children were detailedly analyzed and compared with the pathological results. 【Results】 The tumors occurred in the pancreatic head region in 3 cases, in the pancreatic body region in 5 cases, and in both the pancreatic body and tail regions in 1 case. CT showed mixed-density masses with lobulated shapes; necrosis and calcification were observed in all 9 cases. The masses showed heterogeneous mild enhancement in the arterial phase of enhanced scan, and progressive enhancement in 6 cases. On MRI, the masses presented low signal or intermediate signal intensity on T₁WI and isointense or hyperintense signal intensity on T₂WI, with heterogeneous enhancement after contrast administration; main pancreatic duct dilatation was found in 1 case. Tumors with clear boundaries on imaging usually had relatively complete fibrous capsules on histopathological sections, while those with blurred boundaries often indicated that tumor cells infiltrated into the surrounding tissues with incomplete or absent capsules. The enhancement pattern of tumors on imaging was closely related to the vascular distribution of tumors on histopathological sections. 【Conclusion】Pancreatoblastoma has certain characteristic manifestations on different imaging examinations and is closely correlated with pathological changes. Imaging examinations play an important role in the diagnosis, differential diagnosis and preoperative evaluation of pancreatoblastoma in children. Combining with pathological features can further improve the accuracy and reliability of diagnosis, providing a strong basis for formulating clinical treatment plans.更多还原