【摘要】 目的 基于营养风险筛查2002(NRS-2002)量表对肝硬化并发肌少症患者进行营养风险筛查，并采用多元线性回归对其影响因素进行分析。方法 收集2021年9月至2024年6月于河南省人民医院就诊的294例肝硬化肌少症患者，根据NRS-2002量表将其分为有风险组、无风险组，比较两组一般资料、营养评估，采用logistic回归分析有NRS-2002风险的影响因素。结果 本研究294例肝硬化肌少症患者经NRS-2002量表评估，发现99例患者无营养风险，195例患者存在营养风险，发生率为54.08%;有风险组年龄、白蛋白、血红蛋白、体重指数(BMI)高于无风险组，腹水占比高于无风险组，上臂围、小腿围、三头肌皮褶厚度(TSF)、上臂肌围(AMC)低于无风险组，差异存在统计学意义(P<0.05);logistic回归分析显示，年龄、白蛋白、血红蛋白、BMI是肝硬化肌少症患者存在营养风险的独立影响因素(P<0.05)。结论 年龄、白蛋白、血红蛋白、BMI是肝硬化肌少症患者存在营养风险的独立危险因素，临床可根据NRS-2002量表对肝硬化肌少症患者营养风险进行评估、筛查，改善患者预后。更多还原

【Abstract】 Objective To screen the nutritional risk of patients with liver cirrhosis complicated with sarcopenia based on the nutritional risk screening 2002(NRS-2002) scale,and to analyze the influencing factors by multiple linear regression.Methods A total of 294 patients with cirrhosis and sarcopenia who were treated in Henan Provincial People’s Hospital from September 2021 to June 2024 were collected and divided into a risk group and a non-risk group according to the NRS-2002 scale results. The general information and nutritional assessment of the two groups were compared,and the influencing factors of NRS-2002 risk were analyzed using logistic regression analysis. Results In this study,294 patients with cirrhosis and sarcopenia were evaluated using the NRS-2002 scale. It was found that 99 patients had no nutritional risk,while 195 patients had nutritional risk,with an incidence rate of 54.08%. The age,albumin,hemoglobin,and body mass index(BMI) of the risk group were higher than those of the non-risk group,and the proportion of ascites was higher than that of the non-risk group,the upper arm circumference,calf circumference,triceps skin fold(TSF),and arm muscle circumfer(AMC) were lower than those of the non-risk group,and the differences were statistically significant(P<0.05). Logistic regression analysis showed that age,albumin,hemoglobin,and BMI were independent factors that affected the nutritional risk of patients with cirrhosis and sarcopenia(P<0.05). Conclusion Age,albumin,hemoglobin,and BMI are independent risk factors for nutritional risk in cirrhotic patients with sarcopenia. Clinical assessment and screening of nutritional risk in patients with cirrhosis and sarcopenia can be performed using the NRS-2002 scale to improve patient prognosis.更多还原