【摘要】 目的 探究多模态超声引导下微波消融术(MWA)对甲状腺良性结节(BTN)患者甲状旁腺机能、超声检测值、美观度的影响。方法 选取河南省人民医院2019年5月至2020年6月收治的135例BTN患者，随机分组，超声引导组(68例)行多模态超声引导下MWA,传统手术组(67例)行传统外科手术切除治疗。比较两组手术相关指标、结节吸收情况、甲状腺及甲状旁腺功能[促甲状腺激素(TSH)、甲状旁腺素(PTH)]、美观效果(切口长度及颈部瘢痕长度)、术后并发症发生率。结果 超声引导组术中出血量少于传统手术组，手术及术后住院时间短于传统手术组，切口长度及颈部瘢痕长度短于传统手术组(P<0.05);传统手术组与超声引导组结节治疗愈率差异无统计学意义(P>0.05);超声引导组术后1、3个月血清TSH、PTH水平高于传统手术组(P<0.05);超声引导组术后并发症发生率低于传统手术组(P<0.05)。结论 采用多模态超声引导下MWA治疗BTN患者，结节清除彻底，并发症少，且对甲状旁腺机能影响小，患者切口美观度较高。更多还原

【Abstract】 Objective To investigate the impact of multimodal ultrasound-guided microwave ablation(MWA) on parathyroid function, ultrasound measurements, and aesthetics in patients with benign thyroid nodules(BTN). Methods One hundred and thirty-five patients with BTN were admitted to Henan Province People’s Hospital from May 2019 to June 2020 and randomly divided into two groups. The ultrasound-guided group(68 cases) underwent multimodal ultrasound-guided MWA, while the traditional surgery group(67 cases) received traditional surgical resection. The surgery-related indexes, nodule absorption, thyroid and parathyroid functions [thyroid stimulating hormone(TSH), parathyroid hormone(PTH)], aesthetic results(incision length and neck scar length), and postoperative complication rates were compared between the two groups. Results The ultrasound-guided group had less intraoperative bleeding, shorter operation and postoperative hospitalization times, and shorter incision and neck scar lengths compared to the traditional surgery group(P<0.05). There was no difference in the cure rate of nodules between the traditional surgery group and the ultrasound-guided group(P>0.05). The ultrasound-guided group had higher postoperative serum TSH and PTH levels at 1 and 3 months compared to the traditional surgery group(P<0.05). The incidence of postoperative complications was lower in the ultrasound-guided group than that in the traditional surgery group(P<0.05). Conclusion Patients with BTN treated with MWA under multimodal ultrasound guidance experience complete nodule clearance with minimal impact on parathyroid function. The incisions are aesthetically pleasing, the incidence of postoperative complications is low, and the safety is high.更多还原