【摘要】 目的 探讨胰腺癌化疗患者人格特质的潜在类别，并分析各类别与其心理状况的相关性。方法 选取2022年9月1日—2023年3月1日在川北医学院附属医院行化疗的胰腺癌患者103例为研究对象，采用艾森克人格问卷（Eysenck Personality Questionnaire, EPQ）评估患者的人格特质，采用症状自评量表（Symptom Check List-90, SCL-90）、焦虑自评量表（Self-Rating Anxiety Scale, SAS）、抑郁自评量表（Self-Rating Depression Scale,SDS）评估患者的心理状况，针对胰腺癌化疗患者的人格特质进行潜在剖面分析，并进行多重线性回归分析探讨胰腺癌化疗患者的潜在类别与其心理状况的关系。结果 胰腺癌化疗患者的人格特质可分为低分组（44%）、中等组（27%）、高分组（18%）及极高分组（11%）,SCL-90量表得分、SDS量表得分在人格特质4种类别中均高于临界值，SAS量表得分在人格特质类别的中等组、高分组、极高分组均高于临界值，此外，在不同人格特质类别中胰腺癌化疗患者的SAS得分、SDS得分及SCL-90得分比较差异有统计学意义（P<0.05），年龄、人格特质潜在类别、就诊次数及医疗支付方式是术后SAS量表评分的影响因素（P<0.05），年龄、人格特质潜在类别、就诊次数是术后SDS量表评分的影响因素（P<0.05），年龄、人格特质潜在类别、医疗支付方式及婚姻情况是术后SCL-90量表评分的影响因素（P<0.05）。结论 胰腺癌化疗患者常常存在焦虑、抑郁、人际敏感、敌对等多种心理障碍，且这种心理负向状态在不同人格特质类别群体中表现出异质性，这种异质性表现为，胰腺癌化疗患者的心理负向状态与其人格特质类别由低分组到极高分组呈正相关，了解患者的人格特质类型，可以帮助临床医务人员更好地评估胰腺癌化疗患者的心理健康风险，并采取相应的心理干预措施。更多还原

【Abstract】 Objective To explore the latent categories of personality traits in pancreatic cancer patients undergoing chemotherapy,to analyse the correlation between each category and the psychological status.Methods A total of 103 pancreatic cancer patients undergoing chemotherapy at the Affiliated Hospital of North Sichuan Medical College from 1 September 2022 to 1 March 2023 were selected as the study subjects.The Eysenck Personality Questionnaire(EPQ) was used to assess the patients’ personality traits,and the Symptom Checklist-90(SCL-90),the Self-rating Anxiety Scale(SAS),and the Self-rating Depression Scale(SDS) to assess the psychological status.Latent profile analysis of the personality traits of pancreatic cancer chemotherapy patients and performed multiple linear regression analysis to explore the relationship between the latent categories of pancreatic cancer chemotherapy patients and psychological status.Results The personality traits of pancreatic cancer chemotherapy patients can be divided into low-score group(44%),medium-score group(27%),high-score group(18%),and extremely high-score group(11%).SCL-90 scale scores and SDS scores were above the critical value in all four personality trait categories,SAS scale scores were above the critical value in the moderate,high,and extremely high personality trait categories.Additionally,there were statistically significant differences in SAS scores,SDS scores,and SCL-90 scores among different personality trait categories(P<0.05).Age,personality trait latent categories,number of clinic visits,and medical payment methods were factors influencing post-surgery SAS scores(P<0.05).Age,personality trait latent categories,and number of visits were also significant factors influencing postoperative SDS scores(P<0.05).Age,personality trait latent categories,medical payment methods,and marital status were significant factors influencing postoperative SCL-90 scale scores(P<0.05).Conclusion Patients undergoing chemotherapy for pancreatic cancer often experience multiple psychological disorders such as anxiety,depression,interpersonal sensitivity,and hostility,and this negative psychological state exhibits heterogeneity across different personality trait categories.This heterogeneity is manifested in the fact that the psychological negative state of pancreatic cancer chemotherapy patients is positively correlated with their personality trait categories,ranging from low-score groups to extremely high-score groups.Understanding the personality trait types of patients can help clinical healthcare professionals better assess the psychological health risks of pancreatic cancer chemotherapy patients and implement corresponding psychological intervention measures.更多还原