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血小板分布宽度与急性脑梗死机械取栓术后转归的相关性研究

Correlation Study of Platelet Distribution Width and the Outcome of Patients with Acute Cerebral Infarction after Mechanical Thrombectomy

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【作者】 张夏伟; 冯兵; 何文城; 杨培全; 陈庭军; 韦深记;

【Author】 ZHANG Xiawei;FENG Bing;HE Wencheng;Guangxi Guiping People’s Hospital;

【通讯作者】 何文城;

【机构】 广西壮族自治区桂平市人民医院神经内科;

【摘要】 目的:研究血小板分布宽度与急性脑梗死机械取栓术后转归的相关性。方法:回顾性收集自2022年1月至2024年1月于广西桂平市人民医院行机械取栓术的100例急性脑梗死患者临床资料,根据术后转归分为良好转归组55例[改良Rankin评分(mRS评分)≤2分]和不良转归组45例(mRS评分>2分)。对两组患者的基线资料、PDW值及其他相关临床指标进行分析。结果:不良转归组患者的PDW水平明显高于良好转归组(P<0.05);多因素logistic回归分析,NIHSS评分、血小板分布宽度为术后转归的独立危险因素(均P<0.05)。结论:血小板分布宽度升高可能提示急性脑梗死机械取栓术后不良转归的风险较高,PDW可作为评估术后转归的重要参考指标。

【Abstract】 Objective: To study the correlation between platelet distribution width and the outcome of acute cerebral infarction after mechanical thrombectomy. Methods: The clinical data of 100 patients with acute cerebral infarction who underwent mechanical thrombectomy in Guiping People’s Hospital from January 2022 to January 2024 were retrospectively collected. According to the postoperative outcome, they were divided into the good outcome group [55 cases, modified Rankin score(mRS Score) ≤2] and the poor outcome group(45 cases, mRS Score > 2). The baseline data, PDW value and other relevant clinical indicators of the two groups were analyzed. Results: Results: The PDW level of the patients in the poor outcome group was significantly higher than that in the good outcome group(P<0.05). Multivariate logistic regression analysis showed that NIHSS score and platelet distribution width were independent risk factors for postoperative outcome(all P<0.05). Conclusion: The increased platelet distribution width may indicate a higher risk of poor outcome after mechanical thrombectomy for acute cerebral infarction, and PDW can be used as an important reference index to evaluate the postoperative outcome.

【基金】 广西壮族自治区卫生健康委员会自筹经费科研课题,(编号:Z-R20221964)
  • 【分类号】R743.33
  • 【下载频次】8
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