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1例非特异性间质性肺炎(NSIP)患者免疫抑制剂治疗的临床分析
Clinical Analysis of Immunosuppressive Therapy in a Patient with Nonspecific Interstitial Pneumonia(NSIP)
【摘要】 非特异性间质性肺炎(NSIP)是对肾上腺皮质激素反应较好的一种原发性间质性肺炎,5年内病死率为15%~20%[1]。因此,提高对NSIP的认识,及时采取糖皮质激素治疗,必要时加用其它免疫抑制剂对降低NSIP急性加重期患者的死亡率至关重要。现对1例NSIP患者糖皮质激素联合他克莫司治疗进行分析,旨在协助临床总结用药经验,为今后NSIP患者治疗方案的制定提供药学建议。
【Abstract】 Nonspecific interstitial pneumonia(NSIP) is a type of primary interstitial pneumonia that responds well to adrenocorticotropic hormones, with a mortality rate of 15%-20% within 5 years[1].Therefore, increasing awareness of NSIP,timely glucocorticoid therapy, and the addition of other immunosuppressive agents when necessary are essential to reduce the mortality rate of patients with acute exacerbation of NSIP.Now, we analyze the glucocorticoid combined with tacrolimus treatment in a patient with NSIP,aiming to assist the clinic to summarize the medication experience and provide pharmacological suggestions for the development of future treatment plans for patients with NSIP.
【Key words】 Nonspecific interstitial pneumonia; Glucocorticoids; Tacrolimus;
- 【文献出处】 海峡药学 ,Strait Pharmaceutical Journal , 编辑部邮箱 ,2025年10期
- 【分类号】R979.5
- 【下载频次】38