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基于融合多学科的药物化学综合实验设计与改革

Design and Reform on Comprehensive Experiments in Medicinal Chemistry Based on Integration of Multiple Disciplines

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【作者】 常银霞史静超栾智华魏砚明刘瑞王珂郝志英

【Author】 CHANG Yinxia;SHI Jingchao;LUAN Zhihua;WEI Yanming;LIU Rui;WANG Ke;HAO Zhiying;Shanxi University of Traditional Chinese Medicine;Shanxi Cancer Hospital;

【机构】 山西中医药大学山西省肿瘤医院

【摘要】 坚持理论教学与实验教学相辅相成、贯通融合的理念,我校开展了基于融合多学科的药物化学综合实验设计与改革,建立起包括药物合成、制剂制备、药物分析、药理解析在内的全过程实验流程,并以经典药物“硝苯地平”为例从内容设计、教学方案、课程评价考核3个方面详细解析了药物化学综合实验设计与改革。该实验教学模式有效解决了传统药物化学实验课内容设计、组织操作、仪器配备等方面存在的弊端,是推进教育科技人才一体化教学改革的有益探索。

【Abstract】 Adhering to the concept of complementary and integrated theoretical teaching and experimental teaching, a comprehensive experimental design and reform was launched for Medicinal Chemistry based on the integration of multiple disciplines. A complete experimental process was established, including drug synthesis, formulation preparation, drug analysis and pharmacological analysis. Taking the classic drug “nifedipine” as an example, a detailed analysis of the design and reform was provided for Pharmaceutical Chemistry comprehensive experiments from three aspects: content design, teaching plan, and course evaluation and assessment. This experimental teaching mode effectively solved the drawbacks of traditional Pharmaceutical Chemistry experimental course content design, organizational operation, instrument equipment, etc. It was a beneficial exploration to promote the integrated teaching reform of educational technology talents.

【基金】 山西省自然科学基金项目(No.202203021211218);山西省中医药管理局科研课题(No.2022ZYYC097);山西省教育厅高等学校教学改革创新基金资助项目(No.J20220799);山西省教育厅研究生教育教学改革项目(No.2023JG159);山西省卫健委中医药创新团队科研基金(No.zyytd2024019)
  • 【文献出处】 广州化工 ,Guangzhou Chemical Industry , 编辑部邮箱 ,2025年17期
  • 【分类号】G642;TQ460.1-4
  • 【下载频次】55
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