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消化科首诊的抗SOX1抗体阳性副肿瘤性边缘叶脑炎1例

Paraneoplastic limbic encephalitis with positive anti-SOX1 antibody initially presenting to the department of gastroenterology: a case report

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【作者】 王翠云武力勇张德全叶红

【Author】 WANG Cuiyun;WU Liyong;ZHANG Dequan;YE Hong;Heze Hospital of Traditional Chinese Medicine;Xuanwu Hospital, Capital Medical University;

【通讯作者】 叶红;

【机构】 菏泽市中医医院首都医科大学宣武医院

【摘要】 副肿瘤性边缘叶脑炎常表现为认知障碍、精神行为异常、癫痫发作等症状,临床表现复杂多变,部分患者首诊于非神经科室。该文报道1例首诊于消化科的抗SOX1抗体阳性副肿瘤性边缘叶脑炎患者,并复习相关文献,分析临床及影像学特点,提高对抗SOX1抗体阳性副肿瘤性边缘叶脑炎的认知,尽早识别,以改善患者预后。

【Abstract】 Paraneoplastic limbic encephalitis often manifests as cognitive impairment, psychiatric-behavioral abnormalities, and seizures, with complex and diverse clinical manifestations, and some patients attend non-neurological departments at the first consultation. This article reports a case of paraneoplastic limbic encephalitis with positive anti-SOX1 antibody initially presenting to the department of gastroenterology, and a literature review was also performed to analyze its clinical and imaging features, enhance the awareness of paraneoplastic limbic encephalitis with positive anti-SOX1 antibody, facilitate early identification, and thus improve the prognosis of patients.

  • 【文献出处】 国际神经病学神经外科学杂志 ,Journal of International Neurology and Neurosurgery , 编辑部邮箱 ,2025年04期
  • 【分类号】R739.4
  • 【下载频次】7
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