【摘要】 乳腺癌的发生、发展和转移与肿瘤微环境密切相关。生境成像（HI）可以通过反映瘤内异质性（ITH）来刻画肿瘤微环境，在辅助评估乳腺癌分子特征、亚型鉴别、预测肿瘤治疗反应、评估转移风险与预测预后等方面具有重要价值。简述HI的原理与方法，就其在乳腺癌中的研究进展予以综述，并分析当前的挑战与未来方向，以期为乳腺癌的精准诊断和个体化治疗提供参考。更多还原

【Abstract】 The occurrence, progression, and metastasis of breast cancer are closely associated with the tumor microenvironment. Habitat imaging(HI) can characterize the tumor microenvironment by reflecting intratumoral heterogeneity(ITH), and it holds significant value in assisting the evaluation of molecular characteristics, subtype differentiation, predicting tumor treatment response, assessing metastasis risk, and prognostic prediction in breast cancer.This article briefly explains the principles and methods of HI, reviews the research progress of HI in breast cancer, and analyzes current challenges and future directions, aiming to provide references for the precise diagnosis and personalized treatment of breast cancer.更多还原