【摘要】 为确保光疗期间黄疸新生儿正常的生命体征，设计了一种适用于光疗期间的新生儿多生理参数监测系统。该系统包括硬件和软件两个部分，其中硬件部分包括基于MAX30205的体温模块和基于ADS1292R的心电呼吸模块，使用nRF52832作为主控芯片，采用低功耗蓝牙(Bluetooth Low Energy, BLE)技术实现连续体温(Body Temperature, BT)、心电图(Electrocardiogram, ECG)和呼吸波形图(Respiratory Waveform Graph, RWG)的同步采集和数据传输；软件部分采用LabVIEW进行设计，完成数据显示与存储。采用聚二甲基硅氧烷(Polydimethylsiloxane, PDMS)对体温模块进行柔性封装，通过医用胶带贴于额头或腋下；心电呼吸模块固定在纸尿裤上，其电极贴于胸腹部。在可行性分析中，该系统的硬件电气性能和软件功能得到验证，并在测试对象上完成相关生理参数采集及信号分析。体温模块测量误差小于0.1℃;心电信号信噪比为23.86 dB,呼吸波形与对照设备波形的相关性为0.77;测试范围内丢包率低于0.36%,系统可正常工作24 h左右。该系统满足低功耗、可穿戴和无线通信的要求，为临床优化光疗安全监护提供了参考方案。更多还原

【Abstract】 To ensure normal vital signs in jaundiced newborns during phototherapy, a multi-physiological parameter monitoring system for newborns during phototherapy was designed. The system consists of two parts, hardware and software. The hardware includes a MAX30205-based body temperature module and an ADS1292R-based ECG respiratory module, adopting nRF52832 as the main control chip, and Bluetooth Low Energy(BLE) technology to realize the synchronous acquisition and data transmission of continuous body temperature(BT),electrocardiogram(ECG) and respiratory waveform graph(RWG). The BLE technology was used to synchronize acquisition and data transmission of continuous body temperature, ECG and RWG. The software part is designed by LabVIEW software for data display and data storage. Polydimethylsiloxane(PDMS) was used to flexibly encapsulate the temperature module, which was attached to the forehead or armpit by medical tape, and the cardiac respiratory module was fixed to the diaper with its electrodes attached to the chest and abdomen. In the feasibility analysis, the hardware electrical performance and software function of the system were verified, and the relevant physiological parameters acquisition and signal analysis were completed on the test object. The measurement error of the body temperature module is less than 0.1 ℃; the signal-to-noise ratio of the ECG signal is 23.86 dB,and the correlation between the respiratory waveform and the waveform of the control device is 0.77; the packet loss rate of the transmission within the test range is less than 0.36%,and the system can work normally for about 24 h. The system meets the requirements of low power consumption, wearability and wireless communication, and provides a reference solution for clinical optimization of phototherapy safety monitoring.更多还原