节点文献
高毒力碳青霉烯类耐药肺炎克雷伯菌感染诊治与防控专家共识
Expert consensus on the diagnosis,treatment,prevention,and control of hypervirulent carbapenem-resistant Klebsiella pneumoniae infection
【摘要】 高毒力肺炎克雷伯菌(hypervirulent Klebsiella pneumoniae, hvKP)具有独特的表型特征(如高黏液型、特殊血清型)和基因型特征(如携带特殊的毒力基因),临床致病力强。随着细菌耐药的不断演变,高毒力碳青霉烯类耐药肺炎克雷伯菌(hypervirulent carbapenem-resistant Klebsiella pneumoniae, HCKP)的出现,给全球公共卫生及临床感染治疗与防控带来极大挑战。如何早期识别HCKP感染、及时诊治及防控非常重要。本共识就HCKP流行病学、致病与耐药性、临床特征、实验室检查、预防与控制等方面提出专家建议,供临床诊治与防控参考。
【Abstract】 Hypervirulent Klebsiella pneumoniae(hvKP) exhibits unique phenotypes(such as hypermucoviscosity, specific serotypes) and genotypes(such as carrying specific virulence genes), demonstrating strong clinical pathogenicity. With the bacterial convergence evolution, the emergence of hypervirulent carbapenem-resistant Klebsiella pneumoniae(HCKP) poses significant challenges to global public health, as well as to clinical infection treatment and prevention. Early identification, timely diagnosis and treatment, as well as prevention and control of HCKP infection are crucial needs. This consensus aims to provide expert recommendations on the epidemiology, pathogenicity, antimicrobial resistance, clinical characteristics, laboratory testing, as well as prevention and control of HCKP, serving as a reference for diagnosis, treatment, as well as prevention and control of HCKP infections.
【Key words】 Klebsiella pneumoniae; carbapenem-resistance; hypervirulence; diagnosis and treatment; prevention and control; expert consensus;
- 【文献出处】 中国感染控制杂志 ,Chinese Journal of Infection Control , 编辑部邮箱 ,2025年12期
- 【分类号】R446.5
- 【下载频次】102