【摘要】 目的 了解清晨高血压不同人群危险因素、中医证型的分布特征及与危险因素的相关性。方法 回顾性分析476例清晨高血压患者的一般资料，了解心率增快（>80次/分钟）、吸烟史、高血压家族史、糖耐量异常、高脂血症、高尿酸血症、身体质量指数（BMI）>28 kg/m~2等危险因素及中医证型在不同人群中的分布特征，分析其与危险因素的相关性。结果 单因素分析结果显示：吸烟史、高脂血症、BMI及痰湿壅盛型、阴阳两虚型在不同人群分布中差异有统计学意义（P<0.05）；清晨高血压患者收缩压与舒张压的昼夜节律分布差异有统计学意义（P<0.05）；无序多分类Logistic回归分析显示：与青年组相比，高脂血症（OR=0.430,P<0.05）、BMI(OR=2.755,P<0.05)与清晨高血压中年人群相关。吸烟史与清晨高血压老年人群相关（OR=0.569,P<0.05）。结论 清晨高血压昼夜节律以非杓型和反杓型为主；中医证型以痰湿壅盛型为主；高脂血症、BMI是清晨高血压中年人群的危险因素；吸烟史是清晨高血压老年人群的危险因素。更多还原

【Abstract】 Objective To understand the distribution characteristics of risk factors and traditional Chinese medicine(TCM) type in different populations with early morning hypertension and the correlation with risk factors. Methods The general data of 476 patients with early morning hypertension were retrospectively analyzed to understand the distribution characteristics of risk factors such as increased heart rate(>80 bpm), smoking history, family history of hypertension, abnormal glucose tolerance, hyperlipidemia, hyperuricemia, and body mass index(BMI>28 kg/m~2), and the distribution characteristics of TCM type in different populations, and to analyze the correlation between them and the risk factors. Results The results of univariate analysis showed that there were statistically significant differences in the distribution of smoking history, hyperlipidemia, BMI, phlegm-dampness congestion type, and yin-yang deficiency type among different populations(P<0.05). There was a statistically significant difference in the diurnal rhythm distribution of systolic blood pressure and diastolic blood pressure in patients with morning hypertension(P<0.05). The results of unordered multicategorical Logistic regression analysis showed that compared with the young group, hyperlipidemia(OR=0.430, P<0.05) and BMI(OR=2.755, P<0.05) were associated with the middle-aged population with morning hypertension. Smoking history was associated with the elderly population with morning hypertension(OR=0.569, P<0.05). Conclusion The diurnal rhythm of morning hypertension is mainly dominated by the non-dipper type and reverse dipper type. The TCM type is mainly the phlegm-dampness congestion type, hyperlipidemia and BMI are risk factors for middle-aged people with morning hypertension, smoking history is a risk factor for elderly people with morning hypertension.更多还原