【摘要】 钆塞酸二钠（gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid,Gd-EOB-DTPA）作为肝胆特异性对比剂，在肝脏局灶性病变的磁共振成像（magnetic resonance imaging,MRI）检查中扮演着日益重要的角色。本研究综述了Gd-EOB-DTPA增强MRI技术在早期发现、精确诊断结直肠癌肝转移瘤（colorectal liver metastases,CRLM）以及评估治疗反应方面的应用现状和最新进展。Gd-EOB-DTPA的引入显著提高了对CRLM的检测敏感性，尤其是在直径≤1 cm的小病变中。此外，基于Gd-EOB-DTPA增强MRI的影像组学为CRLM的评估提供了新的视角，通过定量分析影像特征，辅助临床决策。本文归纳总结了Gd-EOB-DTPA增强MRI在CRLM诊疗中的特异性影像表现及优势，为进一步优化患者管理和指导治疗策略提供了科学依据。更多还原

【Abstract】 Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid(Gd-EOB-DTPA),as a hepatobiliary specific contrast agent,plays an increasingly important role in magnetic resonance imaging(MRI)of focal hepatic lesions. This study reviewed the application status and latest progress of Gd-EOB-DTPA enhanced MRI technology in early detection,accurate diagnosis and evaluation of response to treatment of colorectal liver metastases(CRLM). The introduction of Gd-EOB-DTPA significantly improved the detection sensitivity of CRLM,especially in small lesions with a diameter of less than 1 cm. In addition,radiomics based on Gd-EOB-DTPA enhanced MRI provides a new perspective for the evaluation of CRLM and assists clinical decision making through quantitative analysis of image features. This paper summarizes the specific image features and advantages of Gd-EOB-DTPA enhanced MRI in the diagnosis and treatment of CRLM,which provides a scientific basis for further optimizing patient management and guiding treatment strategies.更多还原