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益生菌对猪肠道屏障功能的影响研究概况

Progress on Effect of Probiotics on Porcine Intestinal Barrier Function

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【作者】 张伟; 陈穗莲; 田永宽; 黄云; 吴学祥;

【Author】 ZHANG Wei;CHEN Sui-lian;TIAN Yong-kuan;HUANG Yun;WU Xue-xiang;College of Animal Science,Guizhou University;

【通讯作者】 吴学祥;

【机构】 贵州大学动物科学学院;

【摘要】 猪肠道屏障包括物理屏障、免疫屏障、微生物屏障和化学屏障。猪肠道屏障功能的完整性对于维护肠道免受感染及整体健康至关重要。益生菌能改善猪肠道黏膜形态,增强肠道物理屏障功能;益生菌通过调节肠道免疫因子的表达,提高免疫屏障功能,预防或减轻肠道炎症。益生菌可提高肠道有益菌相对丰度,抑制肠道有害菌繁殖,改善肠道菌群结构;益生菌还可促进肠道黏液分泌及短链脂肪酸的产生,改善肠道微生物屏障和化学屏障功能。论文概述了猪肠道屏障功能及近年来益生菌对猪肠道屏障功能改善作用的研究进展,以期为益生菌在养猪业上的应用提供参考。

【Abstract】 The porcine intestinal barrier includes the physical barrier, the immune barrier, the microbial barrier and the chemical barrier.The integrity of the intestinal barrier function is crucial for protecting the intestine from infection and maintaining overall health.Probiotics can improve the morphological structure of the porcine intestine mucosa and enhance the function of the intestinal physical barrier.By regulating the expression of intestinal immune factors, probiotics elevate the function of the immune barrier, prevente or alleviate intestinal inflammation.Probiotics are able to increase the relative abundance of beneficial bacteria in the intestine, to suppress the proliferation of harmful bacteria, and to improve the structure of the intestinal microbiota.Probiotics also promote the secretion of intestinal mucus and the production of short-chain fatty acids, thereby to improve the microbial and chemical barrier functions of the intestine.This summary provides an overview of the barrier function of the porcine intestine and the research progress of probiotics in improving the intestinal barrier of swine in recent years, in order to provide reference for the application of probiotics in the swine industry.

【关键词】 益生菌; 猪; 肠道屏障;
【Key words】 Probiotics; Swine; Intestinal barrier;
【基金】 贵州省科技计划项目(黔科合支撑[2020]1Y033号,黔科合支撑[2019]2276号)
  • 【文献出处】 动物医学进展 ,Progress in Veterinary Medicine , 编辑部邮箱 ,2025年02期
  • 【分类号】S828.5
  • 【下载频次】239
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