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从营卫理论探讨类风湿关节炎中医诊疗思路
Interpretation of diagnostic and therapeutic approaches of traditional Chinese medicine on rheumatoid arthritis based on Ying-Wei theory
【摘要】 营卫理论是中医原创理论中重要组成部分。营气行于脉中以濡养肌肤,卫气行于脉外抵抗外邪、护卫肌表,营卫之间互相协调方能维持人体正常功能,如营卫失衡则导致免疫代谢紊乱而出现多种疾病。类风湿关节炎是临床常见的难治性自身免疫疾病,发病率高、致残率高但临床缓解率低,其疾病发生、进展与营卫功能密切相关。文章从营卫失调阐释免疫代谢及其节律紊乱对类风湿关节炎疾病发生进展的影响,认为营卫协调运行保持免疫代谢节律稳态与类风湿关节炎疾病活动情况存在相关性,“调和营卫”可作为类风湿关节炎治疗的重要策略,其机制与重塑免疫代谢节律稳态密切相关。
【Abstract】 Ying-Wei theory is an important part of the original theory of traditional Chinese medicine. Ying qi keeps on running in blood vessel to nourish the skin; Wei qi is extravascular to resist external evil and guard the fleshy exterior, and coordination between Ying and Wei can maintain the normal function of the human body, while the imbalance of Ying and Wei may lead to immune metabolism disorders and a variety of diseases. Rheumatoid arthritis is a common and refractory autoimmune disease with high morbidity and disability but low clinical remission. The occurrence and progression of rheumatoid arthritis are closely related to the function of Ying and Wei. Here in this study, the effects of immune metabolism and its rhythm disturbance on the progression of rheumatoid arthritis disease were explained from the perspective of Ying-Wei disorder. And it was believed that the coordinated operation of Ying-Wei to maintain the homeostasis of immune metabolism is correlated with the disease activity of rheumatoid arthritis. ‘Harmonizing Ying-Wei’ could be used as an important strategy for the treatment of rheumatoid arthritis, and its mechanism is closely related to the remodeling rhythm homeostasis of immune metabolism.
【Key words】 Rheumatoid arthritis; Ying-Wei disharmony; Circadian clock gene; Guizhi Shaoyao Zhimu Decoction; Harmonizing Ying-Wei;
- 【文献出处】 中华中医药杂志 ,China Journal of Traditional Chinese Medicine and Pharmacy , 编辑部邮箱 ,2025年06期
- 【分类号】R259
- 【下载频次】64