【摘要】 面对慢性阻塞性肺病（COPD）、心源性肺水肿和阻塞性睡眠呼吸暂停低通气综合征（OSAHS）等多种疾病，亟需无创通气（NIV）面罩。然而，传统NIV面罩存在漏气、适应性不足、二次挫伤病患等问题。本研究以杜仲胶（EUG）为基础，开发出形状记忆特性个性化NIV面罩。采用物理共混法将苯乙烯-乙烯-丁烯-苯乙烯嵌段共聚物（SEBS）填充到杜仲胶中以加快其形状固定速率，制备出一系列硬质EUG-SEBS形状记忆材料；同时，向杜仲胶中添加天然橡胶（NR），制备出一系列软质EUG-NR形状记忆材料，旨在保证复合材料良好的形状固定率的前提下，降低其硬度，结合纯天然橡胶实现硬度梯度逐步降低。实验结果表明：SEBS的用量为5 phr（每百克复合材料所含的质量份数）时，EUG-SEBS复合材料（即EUG-5SEBS）的形状固定率最高，为95.5%；当EUG和NR的质量比为80/20时，复合材料EUG80-NR20的综合性能最佳，其形状固定率为75.78%，邵A硬度为87。由EUG-5SEBS、EUG80-NR20和NR这3种材料制作的个性化无创通气面罩，可满足不同脸型的依顺性和普适性的目标，并对其进行了舒适度调查，结果表明该面罩的舒适度较佳。更多还原

【Abstract】 Faced with multiple diseases such as chronic obstructive pulmonary disease(COPD), cardiogenic pulmonary edema and obstructive sleep apnea-hypopnea syndrome(OSAHS), there is an urgent need for non-invasive ventilation(NIV) masks. Traditional NIV masks have problems such as air leakage, limited adaptability and secondary contusion for patients. A personalized NIV mask with shape memory characteristics based on Eucommia() ulmoides gum EUG has been developed in this study. Styrene-ethylene-butene-styrene block copolymer(SEBS) was filled into Eucommia ulmoides gum by physical blending to accelerate its shape fixation rate, and a series of hard EUG-SEBS shape memory materials were prepared. Meanwhile, natural rubber(NR) was added to Eucommia ulmoides gum to prepare a series of soft EUG-NR shape memory materials. Adding NR gradually reduces the hardness gradient of the composite material while ensuring a high shape-fixation rate. The experimental results show that the shape-fixation rate of EUG-5 SEBS had the highest value of 95.5%; when the mass ratio of EUG to NR was 80/20, the composite material exhibited the best comprehensive performance, with a shape-fixation rate of 75.78% and a Shore A hardness of 87. Layers of rigid polyurethane, EUG-5 SEBS, EUG80-NR20 and NR, were combined to manufacture personalized non-invasive ventilation masks with shape-memory properties to meet the goals of compliance across different face shapes. A comfort survey showed that this mask was more comfortable than conventional airbag masks.更多还原