【摘要】 目的 比较内镜黏膜下剥离术（ESD）与内镜黏膜切除术（EMR）在早期食管癌患者中的应用效果。方法根据手术方式的不同将110例早期食管癌患者分为EMR组（n=54，接受EMR术）和ESD组（n=56，接受ESD术）。比较两组患者手术指标、病灶切除情况、并发症发生情况和复发情况。结果 ESD组患者的手术时间长于EMR组，术中出血量多于EMR组，病灶完全切除率及整块切除率均高于EMR组，差异均有统计学意义（P﹤0.05）。ESD组患者的并发症总发生率为17.86%，高于EMR组患者的5.56%，随访1年复发率为3.57%，低于EMR组患者的18.52%，差异均有统计学意义（P﹤0.05）。结论 相较于EMR术，ESD术可提高早期食管癌患者的病灶切除率，降低复发风险，但术后并发症风险较高。更多还原

【Abstract】 Objective To compare the application effects of endoscopic submucosal dissection(ESD) and endoscopic mucosal resection(EMR) in early esophageal cancer patients. Method According to different surgical methods, 110 patients with early esophageal cancer were divided into EMR group(n=54, receiving EMR surgery) and ESD group(n=56,receiving ESD surgery). The surgical indicators, lesion resection status, incidence of complications, and recurrence status were compared between the two groups. Result The surgical time of ESD group was longer than that of EMR group,the intraoperative blood loss was higher than that of EMR group, the complete lesion resection rate and whole block resection rate were higher than those of EMR group, and the differences were statistically significant(P<0.05). The total incidence of complications in the ESD group was 17.86%, which was higher than 5.56% in the EMR group, the 1-year follow-up recurrence rate was 3.57%, which was lower than 18.52% in the EMR group, and the differences were statistically significant(P<0.05). Conclusion Compared to EMR surgery, ESD surgery can improve the lesion resection rate and reduce the risk of recurrence in early esophageal cancer patients, but the risk of postoperative complications is higher.更多还原