【摘要】 目的 探讨集束化干预联合心理指导在中晚期肺癌化疗患者中的应用效果。方法 根据干预方式的不同将106例中晚期肺癌化疗患者分为对照组(52例,常规干预+心理指导)和观察组(54例,在对照组的基础上采取集束化干预)。比较两组患者的疾病进展恐惧水平[疾病进展恐惧简化量表(FoP-Q-SF)]、生活质量[肺癌患者生存质量测定量表(FACT-L)]、不良反应发生情况及满意度。结果 干预后,两组患者FoP-Q-SF评分均低于本组干预前,观察组患者FoP-Q-SF评分低于对照组,差异均有统计学意义(P<0.05)。干预后,两组患者FACT-L各维度评分及总分均高于本组干预前,观察组患者FACT-L各维度评分及总分均高于对照组,差异均有统计学意义(P<0.05)。观察组患者恶心呕吐、静脉炎、食欲减退发生率均低于对照组,差异均有统计学意义(P<0.05)。观察组患者总满意度高于对照组,差异有统计学意义(P<0.05)。结论 集束化干预联合心理指导可减轻中晚期肺癌化疗患者疾病进展恐惧水平,减少化疗不良反应,改善生活质量,提高满意度。更多还原

【Abstract】 Objective To explore the application effect of cluster intervention combined with psychological guidance in patients with advanced lung cancer undergoing chemotherapy.Method According to different intervention methods,106 patients with advanced lung cancer who underwent chemotherapy were divided into the control group(52 cases,conventional intervention+psychological guidance) and the observation group(54 cases,cluster intervention was adopted on the basis of the control group).The levels of fear of disease progression [fear of progression questionnaire-short form(FoP-Q-SF)],quality of life [functional assessment of cancer therapy-lung(FACT-L)],adverse reactions and satisfaction were compared between the two groups.Result After intervention,the FoP-Q-SF scores of both groups were lower than those before intervention,the FoP-Q-SF score of the observation group was lower than that of the control group,and the differences were statistically significant(P<0.05).After intervention,the scores of each dimension of FACT-L and the total scores in both groups were higher than those before intervention,the scores of each dimension of FACT-L and the total score in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The incidences of nausea and vomiting,phlebitis and anorexia in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The total satisfaction rate in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Cluster intervention combined with psychological guidance can reduce the fear level of disease progression in patients with advanced lung cancer undergoing chemotherapy,decrease adverse reactions of chemotherapy,improve the quality of life and increase satisfaction.更多还原