【摘要】 目的 探讨基于AIDET沟通模式的综合干预对口腔癌患者炎性因子、负性情绪和配合度的影响。方法 依据干预方式的不同将112例口腔癌患者分为对照组（n=51，常规干预）和观察组（n=61，常规干预+基于AIDET沟通模式的综合干预）。比较两组患者的负性情绪[汉密尔顿焦虑量表（HAMA）、汉密尔顿抑郁量表（HAMD）]、炎性因子[C反应蛋白（CRP）、白细胞介素-6(IL-6)]水平、配合度和满意度。结果 干预后，两组患者CRP、IL-6水平均低于本组干预前，观察组患者CRP、IL-6水平均低于对照组，差异均有统计学意义（P﹤0.05）。干预后，两组患者HAMA、HAMD评分均低于本组干预前，观察组患者HAMA、HAMD评分均低于对照组，差异均有统计学意义（P﹤0.05）。干预后，两组患者遵医运动、遵医复查、遵医用药、日常生活注意事项评分均高于本组干预前，观察组患者遵医运动、遵医复查、遵医用药、日常生活注意事项评分均高于对照组，差异均有统计学意义（P﹤0.05）。观察组患者的总满意度为90.16%，高于对照组患者的74.51%，差异有统计学意义（P﹤0.05）。结论 基于AIDET沟通模式的综合干预能够改善口腔癌患者的负性情绪，提高配合度和满意度，降低炎性因子水平。更多还原

【Abstract】 Objective To explore the influence of comprehensive intervention based on AIDET communication mode on inflammatory factors, negative emotions, and cooperation in oral cancer patients. Method A total of 112 oral cancer patients were divided into control group(n=51, conventional intervention) and observation group(n=61, conventional intervention + comprehensive intervention based on AIDET communication mode) according to different intervention methods. The negative emotions [Hamilton anxiety scale(HAMA), Hamilton depression scale(HAMD)], inflammatory factors [C-reactive protein(CRP), interleukin-6(IL-6)], compliance and satisfaction were compared between the two groups. Result After intervention, the levels of CRP and IL-6 in both groups were lower than those before intervention,the levels of CRP and IL-6 in observation group were lower than those in control group, and the differences were statistically significant(P<0.05). After intervention, the HAMA and HAMD scores in both groups were lower than those before intervention, the HAMA and HAMD scores in observation group were lower than those in control group, and the differences were statistically significant(P<0.05). After intervention, the scores of compliance exercise, compliance review,compliance medication, and daily life precautions in both groups were higher than those before intervention, the scores of compliance exercise, compliance review, compliance medication, and daily life precautions in observation group were higher than those in control group, and the differences were statistically significant(P<0.05). The overall satisfaction rate in observation group was 90.16%, which was higher than 74.51% in control group, and the difference was statistically significant(P<0.05). Conclusion The comprehensive intervention based on AIDET communication mode can improve the negative emotions of oral cancer patients, increase cooperation and satisfaction, and reduce the level of inflammatory factors.更多还原