【摘要】 目的 比较水平半喉切除术、环状软骨-舌骨-会厌固定术（CHEP）、垂直半喉切除术治疗喉癌患者的疗效。方法 依据手术方式的不同将160例喉癌患者分为A组（n=50，水平半喉切除术）、B组（n=58,CHEP术）、C组（n=52，垂直半喉切除术），比较3组患者的吞咽功能、嗓音学指标及并发症发生情况。结果 C组患者的吞咽功能优于A组、B组，差异均有统计学意义（P﹤0.05）。C组患者标准化噪声能量、基频微扰、振幅微扰均低于A组、B组，差异均有统计学意义（P﹤0.05）。C组患者的并发症总发生率为3.85%，低于A组患者的18.00%和B组患者的18.97%，差异均有统计学意义（P﹤0.05）。结论 相比于水平半喉切除术、CHEP，垂直半喉切除术有利于喉癌患者吞咽功能的恢复，改善嗓音学指标，降低并发症发生率。更多还原

【Abstract】 Objective To compare the efficacy of horizontal hemilaryngectomy, cricohyoidoepiglottopexy(CHEP),and vertical hemilaryngectomy in the treatment of patients with laryngeal cancer. Method According to different surgical methods, 160 patients with laryngeal cancer were divided into group A(n=50, horizontal hemilaryngectomy), group B(n=58, CHEP surgery), and group C(n=52, vertical hemilaryngectomy). The swallowing function, vocal indicators, and incidence of complications were compared among the three groups. Result The swallowing function in group C was better than those in group A and group B, and the differences were statistically significant(P<0.05). The standardized noise energy, fundamental frequency perturbation and amplitude perturbation in group C were lower than those in group A and group B, and the differences were statistically significant(P<0.05). The total incidence of complications in group C was3.85%, which was lower than 18.00% in group A and 18.97% in group B, and the differences were statistically significant(P<0.05). Conclusion Compared to horizontal hemilaryngectomy and CHEP, the vertical hemilaryngectomy is beneficial for the recovery of swallowing function, improvement of vocal indicators, and reduction of the incidence of complications in patients with laryngeal cancer.更多还原