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人参活性生物大分子的化学结构和有益作用:叙述性综述(英文)

Chemical structure and beneficial roles of active biomacromolecules from Ginseng:a narrative review

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【作者】 李诗璐张帅付璐陈晨张文慧李伟

【Author】 Shi-Lu Li;Shuai Zhang;Lu Fu;Chen Chen;Wen-Hui Zhang;Wei Li;College of Chinese Medicinal Materials, Jilin Provincial International Joint Research Center for the Development and Utilization of Authentic Medicinal Materials, Jilin Agricultural University;College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University;Endocrinology and Metabolism, School of Biomedical Sciences, University of Queensland;

【通讯作者】 张文慧;李伟;

【机构】 中药材学院吉林省道地药材开发利用国际联合研究中心吉林农业大学生命科学学院教育部生物反应器与制药工程研究中心吉林农业大学内分泌与代谢生物医学学院昆士兰大学

【摘要】 源自植物性中药的生物大分子在天然药物研究中发挥着举足轻重的作用。人参(Panax ginseng C.A. Meyer的根)因其多样的药理活性和广泛的治疗应用而备受关注。本综述重点介绍从人参中提取的特定活性大分子,包括果胶、外泌体、蛋白质和膳食纤维。这些成分具有独特的结构特征和生物活性,为人参的多方面应用提供了新的见解。为了系统地评估这一领域,我们回顾了过去60年间发表的文献,确定了119项调查人参生物大分子的结构组成、药理活性和潜在应用的相关研究。本综述强调了人参生物大分子在促进健康和增强抗病能力方面的重要作用,综合了有关人参药理作用的最新研究成果,为临床药物开发提供了新的视角和有力的理论支持。

【Abstract】 Biomacromolecules derived from plant-based traditional Chinese medicines play a pivotal role in natural drug research. Ginseng, the root of Panax ginseng C.A. Meyer, has attracted significant attention due to its diverse pharmacological activities and broad therapeutic applications. This review focuses on specific active macromolecules obtained from ginseng, including pectin, exosomes, proteins, and dietary fibers. These components possess unique structural characteristics and biological activities that offer novel insights into the multifaceted applications of ginseng. To systematically assess this field, we reviewed literature published over the past 60 years and identified 119 relevant studies investigating the structural composition, pharmacological activity, and potential applications of P. ginseng biomacromolecules. By highlighting their crucial role in promoting health and enhancing disease resistance, this review synthesizes the latest research findings on ginseng’s pharmacological effects, providing new perspectives and strong theoretical support for clinical drug development.

【关键词】 人参果胶外泌体蛋白质膳食纤维综述
【Key words】 Dietary fiberExosomesGinsengPectinProteinsReview
【基金】 supported by the grants of the National Natural Science Foundation of China (Grant No. 82474070);Jilin Science & Technology Development Plan (Grant No. 20230204003YY)
  • 【文献出处】 Acupuncture and Herbal Medicine ,针灸和草药(英文) , 编辑部邮箱 ,2025年03期
  • 【分类号】R285
  • 【下载频次】51
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