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21012例新冠肺炎患者短期后遗症:一项横断面研究(英文)

Short-term post-COVID-19 symptoms in 21,012 patients:a cross-sectional study

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【作者】 曹璐佳; 吴晓蕾; 张晨瑶; 王传池; 吕文亮; 刘力; 刘伟; 杨志敏; 石岩; 余曙光; 李灿东; 杨明; 闫幸; 金鑫瑶; 王辉; 郑文科; 庞博; 庞稳泰; 胡镜清; 张俊华;

【Author】 Lujia Cao;Xiaolei Wu;Chenyao Zhang;Chuanchi Wang;Wenliang Lyu;Li Liu;Wei Liu;Zhimin Yang;Yan Shi;Shuguang Yu;Candong Li;Ming Yang;Xing Yan;Xinyao Jin;Hui Wang;Wenke Zheng;Bo Pang;Wentai Pang;Jingqing Hu;Junhua Zhang;Key Laboratory of National Medical Products Administration,Evidence-Based Evaluation of Traditional Chinese Medicine;Chinese Core Outcome Sets Research Center;Evidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine;Tianjin University of Traditional Chinese Medicine;Institute of Epidemic Research, Hubei University of Chinese Medicine;Shaanxi University of Chinese Medicine;Shandong University of Traditional Chinese Medicine;State Key Laboratory of Dampness Syndrome of Chinese Medicine;The Second Affiliated Hospital of Guangzhou University of Chinese Medicine;Liaoning University of Traditional Chinese Medicine;Chengdu University of Traditional Chinese Medicine;Fujian University of Traditional Chinese Medicine;Jiangxi University of Chinese Medicine;

【通讯作者】 胡镜清;张俊华;

【机构】 中医药循证评价重点实验室; 核心指标集研究中心; 天津中医药大学循证医学中心; 天津中医药大学; 湖北中医药大学疫病研究所; 陕西中医药大学; 山东中医药大学; 省部共建中医湿证国家重点实验室; 广州中医药大学第二附属医院; 辽宁中医药大学; 成都中医药大学; 福建中医药大学; 江西中医药大学;

【摘要】 [目的]本研究旨在阐明2022年12月中国实施动态清零政策后,新型冠状病毒感染(COVID-19)康复者的短期症状、持续时间及其影响因素。[方法]采用2023年1月14日至2月1日在中国开展的大规模线上调查数据。研究对象涵盖所有年龄段人群。通过卡方检验和多因素逻辑回归分析确定不同症状的相关影响因素。[结果]研究共纳入来自中国七大区域的21,012名患者(女性占71.22%)。多数患者从症状出现到核酸检测转阴的时间≤10天(72.33%)。症状分布随时间变化呈现差异,其中呼吸系统症状(1-4周)和心理-心脏症状(5-8周)最为常见。多因素分析显示,男性、无合并症、居住于东北和西北地区(与华中地区相比)是症状发生风险降低的独立影响因素,而41-60岁年龄组(与18-40岁相比)可能是潜在风险因素。[结论]COVID-19康复后最常见的短期症状为呼吸系统症状和心理-心脏症状。性别、年龄、地理区域和合并症是短期症状发生的潜在影响因素。

【Abstract】 Objectives: This study aimed to clarify the short-term symptoms, duration, and influencing factors in people recovering from coronavirus disease 2019(COVID-19) after China’s dynamic zero-COVID-19 policy was implemented in December 2022.Methods: We included data from a large-scale on-line survey conducted in China between January 14 and February 1, 2023. Participants were individuals of all ages. Chi-squared tests and multivariate logistic regression analyses were performed to identify factors associated with different symptoms.Results: Overall, 21,012 patients from seven regions of China were included in this study(female: 71.22%). For most patients, the period from symptom onset to a negative nucleic acid test result was ≤10 days(72.33%). The distribution of symptoms varied at different times, with respiratory(1–4 weeks) and psychocardiology(5–8 weeks) symptoms being the most common. Multivariate analysis identified male sex, no comorbidity, and living in northeast and northwest China(compared with central China) as independent factors associated with a lower risk of symptoms, while age(41–60 years) was a possible risk factor(compared with 18–40 years).Conclusions: Short-term respiratory and psychocardiology symptoms were the most common after COVID-19 recovery. Sex, age, geographical region, and comorbidities were potential influencing factors for the development of short-term symptoms.

【基金】 funded by the Young Scientists Fund of the National Natural Science Foundation of China under 82305433, 82305437
  • 【文献出处】 Acupuncture and Herbal Medicine ,针灸和草药(英文) , 编辑部邮箱 ,2025年03期
  • 【分类号】R563.1
  • 【下载频次】33
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