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新型冠状病毒感染合并横纹肌溶解症1例

COVID-19 Infection Complicated with Rhabdomyolysis: A Case Report

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【作者】 裴志超朱函坪孙一晟姚苹苹徐芳沈鑫

【Author】 PEI Zhichao;ZHU Hanping;SUN Yisheng;YAO Pingping;XU Fang;SHEN Xin;Zhejiang Provincial Center for Disease Control and Prevention;Department of Clinical Laboratory, Suqian First Hospital;

【通讯作者】 沈鑫;

【机构】 浙江省疾病预防控制中心微生物所宿迁市第一人民医院医学检验科

【摘要】 患者男,30岁,长期进行高强度训练运动,新型冠状病毒感染后出现全身肌肉酸痛、乏力等症状持续半月余,体力不能支撑体育运动。3个月后患者自觉身体恢复开始进行适应性训练,1周后出现胸闷、肌肉剧烈疼痛、乏力、尿液呈茶色等症状。入院查体:双上肢肌肉压痛,四肢活动正常,未见明显水肿;实验室检查:血浆中肌酸激酶31 007 U/L,血清肌酸激酶同工酶153 U/L,肌红蛋白2170 ng/mL。诊断:横纹肌溶解症。经过补液、碱化尿液等治疗后,患者肝肾功能、心肌酶谱各项指标均下降至正常范围内,遂出院。

【Abstract】 A 30-year-old male, who had been engaged in longterm high-intensity training and exercise, developed muscle aches and fatigue that lasted for half a month after the severe acute respiratory syndrome coronavirus 2 infection. His physical strength could not support sports.After 3 months, he felt that his body recovered and began to carry out adaptive training, and after a week, he developed symptoms such as chest tightness, severe muscle pain, fatigue, and brown urine.Physical examination on admission: muscle tenderness in both upper limbs, normal movement of limbs, no obvious edema; Laboratory tests: creatine kinase in plasma 31 007 U/L, serum creatine kinase-MB isoenzyme 153 U/L, and myoglobin 2 170 ng/mL.Diagnosis: rhabdomyolysis.After rehydration, alkalinization of urine and other treatments, his liver and kidney function and cardiac enzyme spectrum decreased to the normal range, and he was discharged.

【基金】 浙江省医药卫生科技计划项目(2023RC008)
  • 【文献出处】 皮肤科学通报 ,Dermatology Bulletin , 编辑部邮箱 ,2024年02期
  • 【分类号】R511;R685.5
  • 【下载频次】12
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