【摘要】 目的：回顾性分析探肾细胞癌脑转移患者生存预后相关因素。方法：收集2007年1月—2019年6月入院诊断为肾癌脑转移患者42例，通过K-M单因素生存分析及COX多因素回归分析影响肾癌脑转移患者预后相关因素。结果：纳入42例患者，中位总生存期为13.233个月，总生存时间为1.30～133.80个月。采用K-M单因素及COX回归多因素分析显示，患者KPS评分（OR:0.431,95%CI:0.213～0.873,P=0.019）、脑转移数目（OR:3.267,95%CI:1.832～5.585,P<0.001）及SRS(OR:0.198,95%CI:0.091～0.430,P<0.001)为影响患者生存预后的独立预后因素。结论：KPS评分、脑转移数目、SRT为影响患者生存预后的重要因素。更多还原

【Abstract】 Objective: To retrospectively analyze the related factors of survival and prognosis in patients with brain metastasis of renal cell carcinoma.Methods: From January 2007 to June 2019,42 patients with brain metastasis of renal cell carcinoma were collected. The prognostic factors of patients with brain metastasis of renal cell carcinoma were analyzed by K-M univariate survival analysis and COX multivariate regression analysis. Results:A total of 42 patients were included,the median overall survival time was 13.233 months,and the overall survival time was 1.30～133.80 months.K-M univariate and COX regression multivariate analysis showed that KPS score(OR: 0.431,95%CI: 0.213～0.873,P=0.019),number of brain metastases(OR: 3.267,95%CI: 1.832～5.585,P<0.001) and SRS(OR: 0.198,95%CI: 0.091～0.430,P<0.001) were independent prognostic factors affecting the survival and prognosis of patients.. Conclusion: KPS score,number of brain metastases and SRT are important factors affecting the survival and prognosis of patients.更多还原