【摘要】 目的 观察肠风饮内服灌肠治疗宫颈癌放疗后急性放射性直肠炎（ARP）临床疗效。方法 将宫颈癌放疗后ARP患者90例随机分为两组各45例，对照组给予西药灌肠治疗，观察组给予肠风饮内服灌肠治疗；比较两组临床疗效、治疗前后中医证候评分、直肠黏膜评分、Karnofsky功能状态评分、炎症因子指标及不良反应发生情况。结果 观察组治疗总有效率为93.33%，明显高于对照组的73.33%(P <0.05)，治疗后中医证候评分、直肠黏膜评分、炎症因子水平及Karnofsky功能状态评分较对照组明显改善（P <0.05）。结论 肠风饮内服灌肠治疗宫颈癌放疗后ARP可有效控制病情，改善生活质量，并有助于抑制炎症细胞因子表达。更多还原

【Abstract】 Objective:To observe the clinical efficacy of Changfeng Decoction enema in treating acute radiation proctitis(ARP)after cervical cancer radiotherapy. Methods:Ninety ARP patients after cervical cancer radiotherapy were randomly allocated into a control group(45 cases)receiving western medicine enemas and an observation group(45 cases)receiving Changfeng Decoction internal drink and enema. Clinical efficacy,pre-and post-treatment scores of TCM syndromes,rectal mucosa condition,Karnofsky performance status(KPS)scores,levels of inflammatory factors,and incidence of adverse reactions were compared between the two groups. Results:The overall effective rate in the observation group was 93.33%,which was significantly higher than 73.33% in the control group(P < 0.05). After treatment,the observation group demonstrated significantly improved TCM syndrome scores,rectal mucosa scores,inflammatory factor levels,and KPS scores compared with the control group(P < 0.05). Conclusion:Internal drink and enema of Changfeng Decoction enhances quality of life and contributes to suppressing the expression of inflammatory cytokines.更多还原