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除草剂莠去津暴露对人类和其他哺乳动物健康影响的研究进展
Research progress on healthy effects of herbicide atrazine exposure on human and other mammal
【摘要】 目的 莠去津(Atrazine,ATZ)是一种在世界范围内广泛使用的三嗪类除草剂,在有ATZ使用历史的地区水体中均检测到ATZ的残留。如果长期持续超量使用,环境中ATZ及其主要降解物质会通过食物链转移,对人类及其他哺乳动物的生殖发育、内分泌、神经、免疫与遗传系统有潜在的毒性作用,进而诱发癌症。因此,本文主要综述了ATZ暴露对人类及其他哺乳动物生殖发育、内分泌、神经、免疫、遗传系统以及潜在致癌性影响的研究进展,并展望了ATZ使用的环境健康风险,提出了ATZ的环境管理建议,对于进一步加强ATZ的使用具有重要意义。
【Abstract】 Objective Atrazine(ATZ) is a triazine herbicide widely used in the world.Residues of ATZ have been detected in water bodies in regions with a history of ATZ use.If it is used in excess for a long time,ATZ and its main degradation substances in the environment will be transferred through the food chain,which has potential toxic effects on the reproductive development,endocrine,nervous,immune and genetic systems of humans and other mammals,and then induce cancer.Therefore,this paper mainly reviews the research progress of ATZ exposure on human and other mammalian reproductive development,endocrine,nervous,immune,genetic system and potential carcinogenicity,and prospects the environmental health risks of ATZ use,and puts forward environmental management suggestions of ATZ,which is of great significance to further strengthen the use of ATZ.
【Key words】 Atrazine; Environmental health; Reproductive and developmental toxicity; Endocrine disruption; Neurotoxicity; Genotoxicity; Immunotoxicity; Carcinogenicity;
- 【文献出处】 职业与健康 ,Occupation and Health , 编辑部邮箱 ,2024年04期
- 【分类号】R114
- 【下载频次】63