【摘要】 目的 分析浙江省非伤寒沙门菌和副溶血性弧菌引起的急性胃肠炎（AGI）的疾病负担，为食源性疾病防控提供参考。方法 通过浙江省食源性疾病监测系统收集2022年非伤寒沙门菌和副溶血性弧菌检出率资料，换算非伤寒沙门菌和副溶血性弧菌AGI发病数、发病率和就诊数，采用伤残调整寿命年（DALY）分析不同年龄组非伤寒沙门菌和副溶血性弧菌AGI的疾病负担。结果 2022年浙江省非伤寒沙门菌AGI发病数为88.95万例次，发病率为1 352.42/10万，就诊数为32.89万例次，DALY为972.69 (95%CI:771.68～1 164.16)人年，DALY率为1.48 (95%CI:1.17～1.77)/10万；各年龄组中以<5岁组发病率和DALY率最高，分别为3 989.51/10万和13.93 (95%CI:8.67～18.42)/10万。2022年浙江省副溶血性弧菌AGI发病数为63.94万例次，发病率为972.16/10万，就诊数为16.68万例次，DALY为509.30(95%CI:411.75～699.62)人年，DALY率为0.78 (95%CI:0.63～1.06)/10万；各年龄组中以45～<65岁组发病率和DALY率最高，分别为1 383.55/10万和1.27 (95%CI:1.14～1.96)/10万。结论 浙江省非伤寒沙门菌AGI发病率和疾病负担较高；<5岁儿童非伤寒沙门菌AGI和45～<65岁人群副溶血性弧菌AGI需重点监测。更多还原

【Abstract】 Objective To analyze the disease burden of acute gastrointestinal illness(AGI) caused by non-typhoidal Salmonella and Vibrio Parahaemolyticus in Zhejiang Province, so as to provide the reference for the prevention and control of foodborne diseases. Methods The detection rates of non-typhoidal Salmonella and Vibrio parahaemolyticus in 2022were collected through the Zhejiang Foodborne Disease Outbreak Surveillance System. The number of cases, incidence and hospitalizations of AGI caused by non-typhoidal Salmonella and Vibrio parahaemolyticus were calculated. Disability-adjusted life years(DALY) were used to analyze the disease burden of AGI caused by non-typhoidal Salmonella and Vibrio parahaemolyticus among different age groups. Results The number of AGI cases caused by non-typhoidal Salmonella in Zhejiang Province in 2022 was 889 500 person-times, the incidence rate was 1 352.42/10~5, the number of hospital visits was 328 900 person-times, the DALY was 972.69(95%CI: 771.68-1 164.16) person-years, and the DALY rate was 1.48(95%CI: 1.17-1.77)/10~5. The incidence rate and DALY rate were highest in the children aged under 5years, reaching 3 989.51/10~5and 13.93(95%CI: 8.67-18.42)/10~5, respectively. The number of AGI cases caused by Vibrio parahaemolyticus in Zhejiang Province was 639 400 person-times, the incidence rate of 972.16/10~5,the number of hospital visits was 166 800 person-times, the DALY was 509.30(95%CI: 411.75-699.62) person-years, and the DALY rate was 0.78(95%CI: 0.63-1.06)/10~5. The incidence rate and DALY rate were highest in the residents aged 45to <65 years, reaching 1 383.55/10~5and 1.27(95%CI: 1.14-1.96)/10~5, respectively. Conclusions The incidence and DALY of AGI caused by non-typhoidal Salmonella were relatively high in Zhejiang Province. The AGI caused by non-typhoidal Salmonella in the children under 5 years and the AGI caused by Vibrio parahaemolyticus in the residents aged 45to <65 years need to be monitored with priority.更多还原