【摘要】 目的 了解成都市居民血脂异常患病情况及影响因素，为完善血脂异常防制策略提供依据。方法 基于西南区域自然人群队列研究项目的基线调查，于2018年采用多阶段分层整群随机抽样方法抽取成都市5个县（区） 34个乡镇（社区）的30～79岁居民为调查对象，通过问卷调查收集人口学信息、生活行为方式等资料，通过体格检查和实验室检测收集血压、空腹血糖、血尿酸、总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）等指标；采用多因素logistic回归模型分析血脂异常的影响因素。结果 调查21 113人，其中男性9 331人，占44.20%；女性11 782人，占55.80%。年龄为（50.80±12.32）岁。血脂异常7 524例，患病率为35.64%，其中高TG血症、低HDL-C血症、高TC血症和高LDL-C血症患病率分别为17.25%、11.88%、10.11%和7.35%。多因素logistic回归分析结果显示，性别（男，OR=1.584,95%CI:1.463～1.716）、年龄（50～79岁，OR:1.221～1.444,95%CI:1.079～1.632）、居住地（城区，OR=1.123,95%CI:1.052～1.198）、婚姻状况（非在婚，OR=1.246,95%CI:1.128～1.376）、文化程度（高中及以上，OR=0.914,95%CI:0.849～0.983）、吸烟（OR=1.220,95%CI:1.121～1.327）、饮酒（1～2 d/周，OR=1.525,95%CI:1.368～1.700;3～5 d/周，OR=1.857,95%CI:1.575～2.191；几乎每天，OR=1.512,95%CI:1.269～1.801）、业余静坐时间（>2 h/d,OR=1.123,95%CI:1.046～1.206）、中心性肥胖（OR=2.121,95%CI:1.986～2.265）、高血压（OR=1.489,95%CI:1.388～1.598）、糖尿病（OR=1.998,95%CI:1.833～2.157）和高尿酸血症（OR=2.012,95%CI:1.848～2.192）是血脂异常的影响因素。结论 成都市居民血脂异常的影响因素主要有吸烟、饮酒、静坐时间、中心性肥胖、高血压、糖尿病及高尿酸血症等。更多还原

【Abstract】 Objective To investigate the prevalence and influencing factors of dyslipidemia among residents in Chengdu City, so as to provide insights into improving the prevention and control of dyslipidemia. Methods Based on the baseline survey of the Natural Population Cohort Study in Southwest China, residents aged 30 to 79 years was selected from34 towns(communities) in 5 counties(districts) of Chengdu City using the multi-stage stratified cluster random sampling method in 2018. Demographic information and lifestyle behaviors were collected through questionnaires. Blood pressure, fasting blood glucose, serum uric acid, total cholesterol(TC), triglyceride(TG), high-density lipoprotein cholesterol(HDL-C), and low-density lipoprotein cholesterol(LDL-C) were collected through physical examination and laboratory tests. A multivariable logistic regression model was used to identify the factors affecting dyslipidamia. Results A total of 21 113 participants were surveyed, including 9 331 males(44.20%) and 11 782 females(55.80%), and had a mean age of(50.80±12.32) years. The prevalence rate of dyslipidemia was 35.64%, and the prevalence rates of high TG, lowHDL-C, high TC and high LDL-C were 17.25%, 11.88%, 10.11% and 7.35%, respectively. Multivariable logistic regression analysis identified gender(male, OR=1.584, 95%CI: 1.463-1.716), age(50 to 79 years old, OR: 1.221-1.444,95%CI: 1.079-1.632), residence(urban, OR=1.123, 95%CI: 1.052-1.198), marital status(not married, OR=1.246, 95%CI:1.128-1.376), educational level(high school and above, OR=0.914, 95%CI: 0.849-0.983), current smoking(OR=1.220,95%CI: 1.121-1.327), drinking(1 to 2 d/week, OR=1.525, 95%CI: 1.368-1.700; 3 to 5 d/week, OR=1.857, 95%CI:1.575-2.191; almost every day, OR=1.512, 95%CI: 1.269-1.801), sedentary time in leisure time(>2 h/d, OR=1.123,95%CI: 1.046-1.206), central obesity(OR=2.212, 95%CI: 1.986-2.265), hypertension(OR=1.489, 95%CI: 1.388-1.598),diabetes(OR=1.998, 95%CI: 1.833-2.157) and hyperuricemia(OR=2.012, 95%CI: 1.848-2.192) as factors affecting dyslipidemia. Conclusion The prevalence of dyslipidemia among residents in Chengdu City was mainly associated with smoking, drinking, sedentary time, central obesity, hypertension, diabetes and hyperuricemia.更多还原