【摘要】 目的：评估用电子计算机断层扫描（CT）测量支气管壁厚度对老年急性期慢性阻塞性肺疾病（COPD）的诊断价值。方法：回顾性选取2021年5月—2022年5月九江市第一人民医院收治的40例老年急性期COPD患者资料作为观察组，对照组纳入40例同期老年心肺功能正常者的资料。对两组予以CT定量测量及肺功能检查，对比两组右肺上叶尖段及其亚尖段支气管气道壁厚度（WT）、WT与气道外径比（TDR）及气道壁面积（WA），分析观察组不同严重程度患者上述指标与第1秒用力呼气容积（FEV₁）的相关性。结果：观察组右肺上叶尖段、亚尖段支气管的WT、TDR及亚尖段支气管的WA均高于对照组，差异均有统计学意义（P<0.05）。观察组不同严重程度COPD支气管的WT、TDR、WA比较，重度组右肺上叶尖段、亚尖段支气管的WT、右肺上叶尖段支气管的TDR和右肺上叶亚尖段支气管的WA均高于轻度组和中度组，差异均有统计学意义（P<0.05）。Pearson相关性分析显示右肺上叶尖段支气管的WT与FEV₁呈负相关，右肺上叶亚尖段支气管的WT、TDR、WA与FEV₁呈负相关（P<0.05）。结论：老年急性期COPD行CT定量测量，能够反映出支气管壁厚度，帮助判断支气管情况，评估病情严重程度，与肺功能密切相关，能够为COPD的诊断、评估提供可靠的依据。更多还原

【Abstract】 Objective:To assessment the diagnostic value of computer tomography （CT） measurement the bronchial wall thickness of elderly acute chronic obstructive pulmonary disease （COPD）.Method:Data of 40 elderly patients with acute stage of COPD admitted to Jiujiang NO.1 People’s Hospital from May 2021 to May 2022 were retrospectively selected as the observation group,and the data of 40 elderly people with normal cardiopulmonary function during the same period were included in the control group.CT quantitative measurement and pulmonary function test were given in the two groups.The airway wall thickness （WT）,WT to airway diameter ratio （TDR） and airway wall area （WA） of the bronchial apical segment of the upper lobe of right lung and its sub-apical segment were compared between the two groups.The correlation between the above indicators and forced expiratory volume in the first second （FEV₁） in patients with different severity of the observation group was analyzed.Result:The bronchial WT and TDR of the apical and sub-apical segment of the upper lobe of right lung and bronchial WA of in the observation group were higher than those in the control group,the differences were statistically significant（P<0.05）.Different severity of COPD bronchial WT,TDR,WA in the observation group were compared,the bronchial WT of apical segment and sub-apical segment of the upper lobe of right lung,the bronchial TDR of apical segment of the upper lobe of right lung and the bronchial WA of sub-apical segment of the upper lobe of right lung in the serious group were higher than those of mild group and moderate group,the differences were statistically significant （P<0.05）.Pearson correlation analysis showed that the bronchial WT of apical segment of the upper lobe of right lung was negatively correlated with FEV₁,the bronchial WT,TDR,WA of sub-apical segment of the upper lobe of right lung were negatively correlated with FEV₁ （P<0.05）.Conclusion:The elderly patients with acute stage of COPD use CT quantitative measurement can reflect the bronchial wall thickness,help to judge the bronchial condition and assess the severity of the disease,and is closely related to pulmonary function.It can provide a reliable basis for the diagnosis and evaluation of COPD.更多还原