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不同钙与有效磷水平对高产深县猪繁殖性能、血清标志物及OPG-RANKL-RANK信号系统的影响

Effects of different levels of calcium and available phosphorus on reproductive performance, serum markers and OPG-RANKL-RANK signal system of high-yielding Shenxian sows

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【作者】 宋佳纯曹洪战李尚桂若虹刘吉祥刘松瓒芦春莲

【Author】 SONG Jiachun;CAO Hongzhan;LI Shang;GUI Ruohong;LIU Jixiang;LIU Songzan;LU Chunlian;College of Animal Science and Technology,Hebei Agricultural University;

【通讯作者】 芦春莲;

【机构】 河北农业大学动物科技学院

【摘要】 旨在研究不同钙与有效磷水平对高产深县猪繁殖性能、血清标志物及OPG-RANKL-RANK信号系统的影响。试验选择以杜洛克公猪精液人工授精、总产仔数11头及以上的健康深县母猪45头,随机分为5组,每组设9个重复,每个重复1头猪。低水平组钙含量0.55%,有效磷含量0.27%;推荐组钙含量0.63%,有效磷含量0.31%;高水平组Ⅰ钙含量0.71%,有效磷含量0.35%;高水平组Ⅱ钙含量0.79%,有效磷含量0.39%;高水平组Ⅲ钙含量0.87%,有效磷含量0.43%。本试验共进行35 d。结果显示,与推荐组相比,高水平组Ⅲ的钙与有效磷水平显著降低了体质量损失和背膘损失(P<0.05),高水平组Ⅰ的仔猪哺乳期成活率显著升高(P<0.05)。与推荐组相比,高水平组Ⅲ的免疫球蛋白G含量显著下降(P<0.05);与低水平组相比,高水平组Ⅱ的IgM含量显著升高(P<0.05);与推荐组相比,高水平组Ⅱ的甲状旁腺素含量显著下降(P<0.05);低水平组的降钙素含量显著下降(P<0.05),高水平组Ⅱ和Ⅲ的成纤维细胞生长因子23含量显著上升(P<0.05);低水平组的雌激素含量显著上升(P<0.05)。与推荐组相比,高水平组Ⅲ的骨特异性碱性磷酸酶和碱性磷酸酶活性显著下降(P<0.05),低水平组的核因子κB配体受体激活剂含量显著上升(P<0.05)。由此可见,高钙磷水平可以提高哺乳母猪的繁殖性能、免疫球蛋白含量和骨形成水平,其中以钙含量为0.79%,有效磷含量为0.39%时最好。

【Abstract】 The aim of this study was to investigate the effects of calcium and available phosphorus from low level, recommended level to high level on reproductive performance, serum immune indexes, calcium and phosphorus hormone metabolism, bone metabolism and OPG-RANKL-RANK signaling system of high-yielding Shenxian lactating sows.A total of 45 healthy Shenxian sows, which were artificially inseminated with Duroc boars and had a total litter size of 11 or more, were randomly divided into five groups with nine replicates per group and one pig per replicate.The calcium content in the low level group was 0.55%,the available phosphorus content was 0.27%,the calcium content in the recommended group was 0.63%,the available phosphorus content was 0.31%,the calcium content in the high level group Ⅰ was 0.71%,the available phosphorus content was 0.35%,the calcium content in the high level group Ⅱ was 0.79%,the available phosphorus content was 0.39%,and the calcium content in the high level group Ⅲ was 0.87%.The available phosphorus content was 0.43%.The trial was conducted for 35d.Compared with the recommended group,calcium and available phosphorus in high level group Ⅲ significantly reduced body weight loss and backfat loss(P<0.05),and the survival rate of piglets in high level groupⅠ during lactation was significantly increased(P<0.05).Compared with the recommended group,the immunoglobulin G level in the high level groupⅢ was significantly lower,and the IgM content in the high level group Ⅱ was significantly higher than that in the low level group(P<0.05).Compared with the recommended group,the parathyroid hormone in the high level group Ⅱ was significantly decreased(P <0.05);calcitonin in low level group decreased significantly(P <0.05),fibroblast growth factor 23in high level groupⅡandⅢincreased significantly(P<0.05);the level of estrogen in the low level group was significantly increased(P<0.05).Compared with the recommended group,the bone specific alkaline phosphatase and alkaline phosphatase in the high level group Ⅱwere significantly decreased(P<0.05),and the nuclear factorκB ligand receptor activator in the low level group Ⅱ was significantly increased(P<0.05).In conclusion,high Ca and P levels can improve the reproductive performance,immunoglobulin content and bone formation level of lactating sows,and the best is when Ca content is 0.79% and available P content is 0.39%.

【基金】 河北省生猪产业技术体系资助项目(HBCT2018110203)
  • 【文献出处】 中国兽医学报 ,Chinese Journal of Veterinary Science , 编辑部邮箱 ,2024年01期
  • 【分类号】S828
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