【摘要】 目的 了解重庆市土榨植物油中黄曲霉毒素（AF）的污染现状，并评估重庆市居民因摄入土榨植物油暴露于AF的健康风险。方法 随机采集重庆市39个区县的土榨植物油样品进行AF检测。基于2018年中国健康与营养调查项目重庆膳食调查数据，采用简单分布评估法进行膳食暴露评估，采用暴露限值（MOE）和定量肝癌风险法进行风险表征。结果 土榨植物油中AF的总体检出率为7.77%，平均浓度为0.10～0.48μg/kg(LB-UB)，所有样品均未超标。土榨花生油中AF的检出率最高（22.73%,5/22）。重庆市全人群经食用土榨植物油的AF平均暴露量为0.069～0.319 ng/kg·BW/d(LB-UB)，高暴露量（P95）为0.209～0.967 ng/kg·BW/d(LB-UB)。男性与女性的暴露水平无显著差异，不同年龄段人群中2～6岁儿童的平均暴露水平最高（0.132～0.610 ng/kg·BW/d）。全人群的肝癌风险低于1例HCC/（10万人/年），但不同性别和不同年龄段人群的MOE值均低于10 000。结论 重庆市土榨植物油中AF引起的肝癌健康风险较低，但仍存在一定的食品安全潜在风险，应持续监管重点食品的AF污染和降低敏感人群的暴露风险。更多还原

【Abstract】 Objective To investigate the contamination status of aflatoxins(AF) in traditionally-produced vegetable oils in Chongqing and assess the health risk for the population exposed to AF through the consumption of such oil.Methods Samples of traditionally-produced vegetable oils were randomly collected from 39 districts in Chongqing City for AF detection. Based on the dietary data from the 2018 China Health and Nutrition Survey, the simple distributed risk assessment method was applied for dietary exposure assessment. The margin of exposure(MOE) value and quantitative hepatocellular carcinoma(HCC) risk method were used to characterize the risk.Results The detection rate of AF in traditionally-produced vegetable oils was 7. 77%, with an average concentration of 0. 10-0. 48 μg/kg(LB-UB) and zero noncompliance rate. The detection rate of AF in traditionally-produced peanut oil was the highest(22. 73%, 5/22.) The average AF exposure level for the whole population in Chongqing City through the consumption of traditionally-produced vegetable oils ranged from 0. 069 to 0. 319 ng/kg·BW/d(LB-UB), with a high exposure level(P95) of 0. 209～0. 967 ng/kg·BW/d(LB-UB). There was no significant difference in the exposure levels between males and females, but the exposure level of children aged from 2 to 6 years was the highest(0. 132～0. 610 ng/kg·BW/d) among different age groups. The HCC risk was below 1 case of HCC per(100 000 person-year), but the MOE values for different genders and age groups were all below 10 000.Conclusion The health risk of HCC caused by exposure to AF in traditionally-produced vegetable oils in the population of Chongqing is relatively low, but there is still potential food safety risk. Continuous monitoring of AF contamination in key foods and efforts to reduce exposure risks for sensitive populations should be prioritized.更多还原