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糖基化在乙型肝炎病毒感染过程中的临床价值
Clinical value of glycosylation in the process of hepatitis B virus infection
【摘要】 糖基化作为蛋白质重要的翻译后修饰,在乙型肝炎病毒(hepatitis B,HBV)识别肝细胞受体、肝细胞内复制、分泌和免疫逃逸等过程中起着重要的作用。研究HBV相关的糖基化修饰,不仅可以揭示HBV与宿主细胞的相互作用机制,也为HBV感染的治疗和干预提供了新的视角。本文总结了HBV感染过程中糖基化作用、相关功能及应用等研究进展。
【Abstract】 Glycosylation, as an important post translational modification of proteins, plays an important role in hepatitis B virus(HBV) signal recognition, intra-hepatocyte replication, secretion and immune escape. Investigating HBV-related glycosylation not only reveals the interaction mechanism between HBV and host cells, but also provides a new perspective for the treatment and intervention of HBV infection. This review summarized the progress of glycosylation, related functions, and potential applications in the process of HBV infection.
- 【文献出处】 中国病毒病杂志 ,Chinese Journal of Viral Diseases , 编辑部邮箱 ,2024年03期
- 【分类号】R512.62
- 【下载频次】35