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梗阻性肥厚型心肌病治疗新进展

New advances in the treatment of hypertrophic obstructive cardiomyopathy

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【作者】 柳叶; 吴强;

【Author】 LIU Ye;WU Qiang;Graduate School of Guizhou Medical University;Department of Cardiology,Guizhou Provincial People’s Hospital;

【通讯作者】 吴强;

【机构】 贵州医科大学研究生院; 贵州省人民医院心血管内科;

【摘要】 在梗阻性肥厚型心肌病(HOCM)的治疗中,传统药物治疗虽能改善患者症状,但未能针对其发病机制延缓自然病程,存在局限性。外科室间隔心肌切除术疗效确切,却因创伤大、风险高而限制了其在临床上的广泛应用。同样,酒精室间隔消融术作为一种微创治疗手段,术后导致的房室传导阻滞等并发症也不容忽视。随着医学技术的不断进步,HOCM的治疗策略也在不断发展。本文旨在概述HOCM治疗领域的新进展。

【Abstract】 In the treatment of hypertrophic obstructive cardiomyopathy(HOCM),traditional pharmacotherapy,while palliative for symptoms,fails to target the pathogenic mechanisms to retard the natural progression of the disease,thus exhibiting limitations in management. Although surgical septal myectomy offers definitive therapeutic outcomes,its widespread clinical application is constrained due to the signif icant invasiveness and elevated risk associated with the procedure. Similarly,the minimally invasive approach of alcohol septal ablation,while a less aggressive treatment option,cannot overlook the potential post-procedural complications such as atrioventricular block. With the continuous advancement of medical technology,treatment strategies for HOCM are evolving. This article aims to provide an overview of the recent advancements in the management of HOCM.

【基金】 贵州省科技平台及人才团队计划项目[黔科合平台人才(2017)5405]
  • 【文献出处】 中国介入心脏病学杂志 ,Chinese Journal of Interventional Cardiology , 编辑部邮箱 ,2024年11期
  • 【分类号】R542.2
  • 【下载频次】10
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