【摘要】 布鲁克公司生产的基质辅助解析/电离-飞行时间质谱仪(MALDI-TOF MS)具有测试快速、准确、灵敏度高、检测范围广等优点。在实际使用中，MALDI-TOF MS的管理和维护对于测试结果的可靠性和仪器安全稳定运行至关重要。介绍了MALDI-TOF MS的工作原理和基质、制样和实验室环境要求，总结了使用过程中遇到的问题并提出了解决方案。更多还原

【Abstract】 Matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) produced by Bruker has advantages of high testing speed,accuracy,high sensitivity,and wide detection range.In practice,the management and maintenance of MALDI-TOF MS is crucial to the reliability of test results and the safe and stable operation of MALDI-TOF MS.The working principle and matrix,requirements of sample preparation and laboratory environment of MALDI-TOF MS are introduced.The problems encountered in the use process are summarized and the solutions are put forward.更多还原