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泡型棘球蚴病的免疫预防现状
The status in the research of immunoprophylaxis of alveolar echinococcosis
【摘要】 多房棘球绦虫感染导致的泡型棘球蚴病是一种严重危害人类健康的人兽共患寄生虫病,采用疫苗防治该病是当前研究的热点之一。EmII/3、Em14-3-3、EMY162、TSP3、CRT、EmLDH、GluT1和TPx蛋白是几种常见的疫苗候选分子,Em疫苗的种类有死疫苗、DNA疫苗、重组抗原、表位肽和载体介导疫苗等。本文将对这方面的研究现状进行综述。
【Abstract】 Alveolar echinococcosis, its pathogen agent is Echinococcus multilocularis,is one type of zoonosis seriously endandering human health, it recently becomes highlight to control this disease by use of the vaccine. EmⅡ/3,Em14-3-3,EMY162,TSP3,CRT,EmLDH,GluT1 and TPx are many kinds of effective candidate molecules of vaccine, Em vaccines include death vaccine, DNA vaccine, recombinant protein, epitope peptides, vector_based vaccine. The review outlines the status in the research of immunoprophylaxis of alveolar echinococcosis.
【关键词】 泡型棘球蚴病;
多房棘球绦虫;
疫苗;
综述;
【Key words】 alveolar echinococcosis; Echinococcus multilocularis; vaccine; review;
【Key words】 alveolar echinococcosis; Echinococcus multilocularis; vaccine; review;
【基金】 国家自然科学基金项目(No.30801052,30671835,30500423,30200239)
- 【文献出处】 中国病原生物学杂志 ,Journal of Pathogen Biology , 编辑部邮箱 ,2024年01期
- 【分类号】R532.32
- 【下载频次】40