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2013-2023年中医药治疗溃疡性结肠炎的文献计量学分析

Traditional Chinese medicine in the treatment of ulcerative colitis in 2013-2023: a bibliometric analysis

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【作者】 曾铖顾思臻黄诗韵窦丹波

【Author】 ZENG Cheng;GU Sizhen;HUANG Shiyun;DOU Danbo;Dept. of Traditional Medicine, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;

【通讯作者】 窦丹波;

【机构】 上海中医药大学附属曙光医院传统医学科

【摘要】 目的 利用文献计量学方法分析中医药治疗溃疡性结肠炎(UC)的研究现状及热点。方法 检索2013年1月至2023年4月中国知网核心期刊数据库及Web of Science核心合集数据库内中医药治疗UC的临床研究、基础研究和药理学研究等文献,利用CiteSpace 6.1.R6软件对纳入文献的作者、机构、关键词等进行文献计量学分析,并绘制可视化图谱。结果 共纳入中文文献1 060篇,英文文献555篇。2013-2023年,中医药治疗UC的相关研究发文量总体呈上升趋势;纳入文献中,中文核心作者有59位,英文核心作者有33位,且形成了以多个关键学者为中心的稳定团体。中文研究热点集中在名医经验、经典名方等方面,英文研究热点集中在细胞、表达、激活、信号通路等方面。肠道菌群、炎症因子等机制方面的研究在中英文文献中均备受关注。结论近年来,中医药领域中UC的相关研究已取得一定进步。未来相关学者应在保持中医药特色的基础上加强临床研究方案的顶层设计,重视中医药治疗UC的长期疗效评价,并应积极利用代谢组学、蛋白质测序等新技术探索中药配伍治疗疾病的科学内涵。

【Abstract】 OBJECTIVE To analyze the current research status and hotspots of traditional Chinese medicine(TCM) in the treatment of ulcerative colitis(UC) via bibliometrics method. METHODS The clinical, basic, and pharmacological research of TCM in the treatment of UC in the CNKI core journals database and Web of Science core collection database were searched from January 2013 to April 2023. The Cite Space 6.1. R6 software was adopted to analyze the number of authors, institutions and keywords. What’s more, a visual map was plotted. RESULTS Overall, 1 060 Chinese articles and 555 English articles were included. In 2013-2023, the number of relevant research documents issued by TCM in the treatment of UC has shown a significant upward trend. Among the included literature, there are 59 core authors in Chinese and 33 core authors in English. A stable group centered on multiple key scholars has been formed. Chinese research hotspots focus on the experience of famous doctors, classical famous prescriptions, etc.; English research hotspots center on cells, expression, activation,signaling pathway, etc. The study of intestinal flora, inflammatory factors, and other mechanisms has attracted much attention in both Chinese and English literature. CONCLUSIONS In recent years, some progress has been made in the study of treating UC with TCM. In the future, the top-level design of clinical research protocols based on maintaining the characteristics of TCM should be strengthened. Moreover, the longterm efficacy evaluation of TCM in the treatment of UC should be emphasized, and new technologies such as metabolomics and protein sequencing should be actively adopted to explore the scientific connotation of TCM compatibility in treating diseases.

【基金】 国家自然科学基金项目(No.82174288);上海市“科技创新行动计划”医学创新研究专项(No.20Y21901900);上海市科技计划项目(No.22S21903500);上海市“医苑新星”青年医学人才培养资助计划(No.沪卫计人事[2019]72号)
  • 【分类号】R259;G353.1
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