【摘要】 目的 探讨宫颈弹性成像术(E-cervix)对多囊卵巢综合征(PCOS)患者宫颈机能的评价及临床价值。方法 采取回顾性研究，选择100例妊娠中晚期出现流产或早产征象的PCOS患者临床资料作为研究对象。根据患者是否合并宫颈功能不全(CI)进行分组，将并发CI患者临床资料纳入POCS-CI组(n=34),将未合并CI患者临床资料纳入POCS-非CI合并组(n=66)。结果 POCS-CI组孕前体质量指数、T、ECI、IOS、IOS/EOS水平高于POCS-非CI合并组，CL、HR低于POCS-非CI合并组(P<0.05);二元Logistic回归分析结果显示，孕前体质量指数、T、ECI、IOS/EOS高水平是POCS患者并发CI的危险因素(OR=1.408、1.465、3.600、85.974,P<0.05);CL、HR高水平是POCS患者并发CI的保护因素(OR=0.088、0.906,P<0.05);绘制ROC曲线结果显示，T、CL、ECI、IOS/EOS、HR及联合检验预测POCS患者并发CI的AUC分别为0.706、0.714、0.640、0.775、0.744、0.952,其中联合检测价值最高。结论 宫颈弹性成像术能够有效预测PCOS患者CI发生风险，其中孕前体质量指数、T、ECI、IOS/EOS、CL、HR是PCOS伴CI的影响因素。更多还原

【Abstract】 Objective To investigate the evaluation and clinical value of cervical elastography(E-cervix) on cervical function in patients with polycystic ovary syndrome(PCOS). Methods A retrospective study was conducted to select the clinical data of 100 PCOS patients with signs of abortion or premature delivery in the middle and late pregnancy as the research objects. The clinical data of patients with cervical insufficiency(CI) were included in the POCS-CI group(n=34), and the clinical data of patients without CI were included in the POCS-non CI group(n=66). Results The pre-pregnancy body mass index, T, ECI, IOS and IOS/EOS levels in the POCS-CI group were higher than those in the POCS-non CI combined group, and CL and HR were lower than those in the POCS-non CI combined group(P<0.05); Binary Logistic regression analysis showed that pre-pregnancy body mass index, T, ECI, and high IOS/EOS levels were risk factors for CI in POCS patients(OR=1.408, 1.465, 3.600, 85.974, P<0.05). The high levels of CL and HR were the protective factors of CI in POCS patients(OR=0.088, 0.906, P<0.05).The results of ROC curve showed that the AUC of T, CL, ECI, IOS/EOS, HR and combined test for predicting CI in POCS patients were 0.706, 0.714, 0.640, 0.775, 0.744 and 0.952, respectively, and the combined test had the highest value. The decision curve was drawn. Conclusions Cervical elastography can effectively predict the risk of CI in PCOS patients. Pre-pregnancy body mass index, T, ECI, IOS/EOS, CL and HR are the influencing factors of CI in PCOS patients.更多还原