【摘要】 目的 探讨合肥市居民不同膳食模式与血脂异常的关联，为该地区血脂异常的防控提供科学依据。方法 采用多阶段分层整群随机抽样方法，对合肥市五个区县的10 024名≥18岁常住居民进行问卷调查和体格检查。其中膳食情况使用半定量食物频率表并采用因子分析法建立了多元膳食模式、加工食品模式、咸菜蛋类模式以及粮谷蔬菜类模式。将四类膳食模式按照因子得分进行四分位分组（G1-G4）并以G1水平为参数，最后通过Logistic回归分析探讨不同膳食模式与四类血脂异常患病率的关系。结果 调查对象的血脂异常总患病率为32.24%，其中高胆固醇（total cholesterol,TC）、高甘油三酯（triacylglycerol,TG）、低高密度脂蛋白胆固醇（highdensitylipoprotein-cholesterol,HDL-C）和高低密度脂蛋白胆固醇（low density lipoprotein-cholesterol,LDL-C）分别占5.04%、10.56%、13.20%和3.44%。调整多个混杂因素后，Logistic回归分析结果显示，多元膳食模式与高LDL-C血症患病风险呈负相关（G4:OR=0.658,95%CI:0.469～0.924)；加工食品模式是血脂异常的危险因素，与高TC、低HDL-C和高LDL-C血症患病风险均呈正相关(G4:OR=1.326,95%CI:1.031～1.705;OR=1.253,95%CI:1.056～1.486和OR=1.401,95%CI:1.05～1.868)；粮谷蔬菜模式与高TC、高TG血症患病风险呈负相关(G2:OR=0.716,95%CI:0.549～0.933;OR=0.796,95%CI:0.657～0.964)。结论 不同膳食模式与血脂异常之间存在关联，居民在日常饮食中应减少油炸等加工食品的摄入，增加粮谷、蔬菜摄入并坚持均衡的多元膳食模式。[营养学报，2024,46(6):540-546]更多还原

【Abstract】 Objective To explore the association between dietary patterns and dyslipidemia in adult residents of Hefei City, and to provide scientific basis for the prevention and control of dyslipidemia in this region. Methods A multi-stage stratified cluster random sampling method was used to conduct a questionnaire survey and physical examination among 10 024 permanent residents aged ≥18 years in five districts and counties of Hefei City. The dietary intakes were analyzed using a semi-quantitative food frequency table. Four dietary patterns were established, including multivariate dietary pattern,processed food pattern, salted vegetable and egg pattern, and cereal and vegetable pattern. Then the four dietary patterns were grouped into four quartiles according to the factor scores(G1-G4) and parameterized by the G1. Finally, the relationship between different dietary patterns and the prevalence of dyslipidemia in the four categories was explored by logistic regression analysis. Results The total prevalence of dyslipidemia among the survey respondents was 32.24%, with hypercholesterolemia, hypertriglyceridemia, hypo-HDL cholesterolemia and hyper-LDL cholesterolemia accounting for 5.04%, 10.56%, 13.20% and 3.44%, respectively. After adjusting for several confounders, logistic regression analysis showed that multivariate dietary pattern was negatively associated with the risk of hyper-LDL cholesterolemia(G4: OR=0.658, 95%CI: 0.469-0.924). Processed food pattern was a risk factor for dyslipidemia, and positively associated with the risk of hypercholesterolemia, hypo-HDL cholesterolemia, and hyper-LDL cholesterolemia( G4: OR=1.326, 95% CI: 1.031-1.705;OR=1.253, 95% CI: 1.056-1.486 and OR=1.401, 95% CI: 1.05-1.868 respectively). Grain and vegetable pattern was negatively associated with the risk of hypercholesterolemia and hypertriglyceridemia(G2: OR=0.716, 95% CI: 0.549-0.933;OR=0.796, 95% CI: 0.657-0.964). Conclusion There is an association between dietary patterns and dyslipidemia. Residents should reduce the intake of fried and other processed foods, increase the intake of grains, cereals and vegetables and adhere to a balanced and diversified dietary pattern in their daily diet. [ACTA NUTRIMENTA SINICA,2024,46(6):540-546]更多还原