【摘要】 目的：评价妊娠期新型冠状病毒(SARS-CoV-2)感染临床实践指南的方法学质量及报告质量，筛选高质量指南，为后期临床实践及指南的制定提供参考意见。方法：系统检索PubMed、中国知网、维普数据库、万方数据库、英国国家卫生与临床优化研究所等数据库，同时补充检索医脉通、用药助手等临床指南APP,收集2019年至2023年3月发布的妊娠期SARS-CoV-2感染相关临床实践指南。使用临床指南研究与评价系统Ⅱ(AGREEⅡ)指南评估和国际实践指南报告标准(RIGHT)检查表，评估符合条件的临床实践指南的方法和报告质量，计算评审者对组内相关系数(ICC)的总体一致性。结果：共纳入15份妊娠期SARS-CoV-2感染临床实践指南，其中国外指南14份，国内指南1份。每个领域的评审人员的总体一致性是可以接受的，根据AGREEⅡ评估，就报告质量而言，临床实践指南所有6个领域的平均报告率为56.42%,其中领域1“范围和目的”的报告率最高(80.37%),领域5“适用性”的报告率最低(36.05%)。所有指南中，RIGHT项目的平均报告率为38.19%。结论：妊娠期SARS-CoV-2感染临床实践指南的质量有待提高，未来指南在制定时需要依靠标准的循证方法和工具，为临床决策提供该领域的高质量指南。更多还原

【Abstract】 OBJECTIVE: To evaluate the methodological and reporting quality of clinical practice guidelines for SARS-CoV-2 infection during pregnancy, and to screen for high quality guidelines, so as to provide references for subsequent clinical practice and guideline development. METHODS: Clinical practice guidelines related to SARS-CoV-2 infection during pregnancy published form 2019 to Mar. 2023 were collected by systematically retrieving databases including PubMed, CNKI, VIP, Wanfang Data, the National Institute for Health and Clinical Excellence of UK, and clinical guideline APP such as Yimaitong and Medication Assistants. The Appraisal of Guidelines for Research and Evaluation Ⅱ(AGREEⅡ) guideline and Reporting Items for Practice Guidelines in Healthcare(RIGHT) checklist were used to assess the methodological and reporting quality of eligible clinical practice guidelines, and the overall consistency of reviewers on the intra-group correlation coefficients(ICC) was calculated. RESULTS: A total of 15 clinical practice guidelines related to SARS-CoV-2 infection during pregnancy were enrolled, including 14 foreign guidelines and 1 domestic guideline. The overall consistency of the reviewers in each area was acceptable, according to AGREEⅡ assessment, in terms of reporting quality, the average reporting rate for all the six areas in clinical practice guidelines was 56.42%, of which the “scope and purpose” of area 1 had the highest reporting rate(80.37%) and the “applicability” of area 5 had the lowest reporting rate(36.05%). The average reporting rate for RIGHT items of all the guidelines was 38.19%. CONCLUSIONS: The quality of clinical practice guidelines for SARS-CoV-2 infection during pregnancy needs to be improved, and future guidelines need to rely on standard evidence-based methods and tools in their development, so as to provide high-quality guidelines for clinical decision-making in this area.更多还原