【摘要】 目的 为临床合理应用局部抗青光眼药品提供参考。方法 通过医院信息系统（HIS）提取某眼科医院2019年至2022年的局部抗青光眼药品使用数据，包括药品种数、单价、规格、使用数量、使用金额。采用限定日剂量（DDD）法回顾性分析该类药物的使用金额、用药频度（DDDs）、限定日费用（DDC）、排序比[药品使用金额排序（B）/DDDs排序（A）]。结果 2019年至2022年，该院前列腺素衍生物使用金额均排名第1，占比均大于60%。曲伏噻吗滴眼液（进口）、曲伏前列素滴眼液（进口）、拉坦前列素滴眼液（进口）的DDC均较高；除他氟前列素滴眼液外，其余前列腺素衍生物类滴眼液的B/A值均小于1。2021年至2022年，布林佐胺噻吗洛尔滴眼液（进口）的DDDs均排名第1。结论 该院局部抗青光眼药品使用趋势符合相关指南推荐，其临床使用相对合理。更多还原

【Abstract】 Objective To provide a reference for the rational application of topical glaucoma medications in the clinic.Methods The data related to the application of topical glaucoma medications in an eye hospital from 2019 to 2022 were extracted from the Hospital Information System (HIS),including drug variety,unit price,specification,use amount and consumption sum.The consumption sum,defined daily dose system (DDDs),defined daily cost (DDC) and ranking ratio[drug consumption sum ranking(B）/DDDs ranking (A)]of these drugs were analyzed retrospectively by the defined daily dose (DDD) method.Results The consumption sum of prostaglandin analogues in the hospital was the most from 2019 to 2022,accounting for more than 60%.The DDCs of imported Travoprost and Timolol Maleate Eye Drops,Travoprost Eye Drops and Latanoprost Eye Drops were all relatively high;the B/A values of prostaglandin analogue eye drops were all lower than one,except for Tafluprost Eye Drops.The DDDs of imported Brinzolamide and Timolol Maleate Eye Drops were the highest from 2021 to 2022.Conclusion The application of topical glaucoma medications in this hospital is in line with the recommendations of relevant guidelines,and their clinical use is relatively rational.更多还原