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甲状腺微小乳头状癌热消融治疗演变及展望

Evolution and prospect of thermal ablation therapy for papillary thyroid microcarcinoma

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【作者】 晏如意; 田友东; 周玲燕; 程艳; 张国辉; 袁盛兴; 肖本龙; 徐栋;

【Author】 YAN Ruyi;TIAN Youdong;ZHOU Lingyan;CHENG Yan;ZHANG Guohui;YUAN Shengxing;XIAO Benlong;XU Dong;Department of Ultrasound, Qujing Municipal First People’s Hospital;Department of Medical Imaging Center, Qujing Municipal First People’s Hospital;Department of Ultrasound, Zhejiang Cancer Hospital;Wenling Big Data and Artificial Intelligence Institute in Medicine;Department of Interventional and Minimally Invasive Surgery, Taizhou Campus of Zhejiang Cancer Hospital (Taizhou Cancer Hospital);Taizhou Key Laboratory of Minimally Invasive Interventional Therapy & Artificial Intelligence;

【通讯作者】 徐栋;

【机构】 曲靖市第一人民医院超声科; 曲靖市第一人民医院医学影像中心; 浙江省肿瘤医院超声医学科; 温岭市医学大数据与人工智能研究院; 浙江省肿瘤医院台州院区(台州市肿瘤医院)介入与微创外科; 台州市微创介入和大数据人工智能重点实验室;

【摘要】 随着甲状腺微小乳头状癌(papillary thyroid microcarcinoma,PTMC)的检出率日益增高,其治疗手段日新月异,近年来一些代替手术治疗的方案逐渐被提出及实践,本文总结并分析PTMC治疗的演变进程、当前状态、趋势和面临的关键问题。从手术方式的转变到主动监测概念的提出,再到热消融方式的广泛应用,通过对比分析,可知热消融是一种很有前途的替代治疗方案,然而,目前对PTMC热消融的适应证已经不能契合个体化、多学科和多模式治疗的理念,本文通过对甲状腺癌热消融治疗的现状及研究进展进行总结,旨在为PTMC热消融适应证之外的临床研究拓展新的视角,并为未来的研究发展指明方向。

【Abstract】 With the increasing detection rate of papillary thyroid microcarcinoma(PTMC), the treatment methods are changing rapidly, especially in recent years, some alternatives to surgical treatment have been gradually put forward and practiced. This paper summarized and analyzed the evolution process, current state, trend and key issues of PTMC treatment. From the way of surgery to the concept of active surveillance, to the wide application of thermal ablation. Through comparative analysis, thermal ablation is a promising alternative treatment. However, the indications for PTMC thermal ablation cannot meet the concept of individualized,multidisciplinary and multimodal treatment. By summarizing the status of thyroid cancer thermal ablation and research progress, this article provided a new perspective for the clinical research outside PTMC thermal ablation indications, and provided direction for future research development.

【基金】 国家自然科学基金(82071946);浙江省“尖兵”“领雁”研发攻关计划(2023C04039)
  • 【分类号】R736.1
  • 【下载频次】48
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