【摘要】 目的 分析山西省10所医疗机构中药配方颗粒使用情况，为临床合理应用和开发提供参考依据。方法 采集山西省中药配方颗粒使用前10位的医疗机构2021年1月至2023年6月门诊开具的中药配方颗粒处方，用Excel 2013统计分析患者年龄分布、处方占比、处方金额、不合理用药情况。选取同期诊断为胃脘痛且服用过半夏泻心汤治疗的患者，采用随机数字表法随机抽取300例作为研究对象，按照用药剂型，将使用传统中药饮片的150例患者作为对照组，使用中药配方颗粒的150例患者作为研究组，比较2组患者的服药依从性及服药后的不良反应发生率。结果 使用中药配方颗粒的患者年龄以21～50岁居多，占85.42%；处方金额301～500元居多，占49.76%；入选的300例胃脘痛患者中，研究组患者服药依从性高于对照组，服药后的不良反应低于对照组，差异有统计学意义（P<0.05）。结论 中药配方颗粒在临床应用中具有明显的优势，但使用价格偏高，需要进一步找到合理的解决方法，为中药配方颗粒更好的发展创造条件。更多还原

【Abstract】 Objective To analyze the usage of Chinese herbal formula granules in 10 medical institutions in Shanxi Province, and provide reference for clinical rational application and development. Methods The prescriptions of traditional Chinese herbal formula granules issued by the top 10 medical institutions in Shanxi Province from January 2021 to June 2023 were collected, and Excel 2013 was used to statistically analyze the patient′s age distribution, prescription proportion, prescription amount, and unreasonable medication situations. A total of 300 patients diagnosed with epigastric pain during the same period and treated with Banxia Xiexin Tang were randomly selected as the study subjects. According to different dosage forms, 150 patients treated with traditional Chinese medicine decoction pieces were as the control group, and 150 patients treated with Chinese herbal formula granules were as the study group. The medication compliance and the incidence of adverse reac-tions after medication were compared between the two groups. Results The majority of the patients using Chinese herbal formula granules were aged between 21 and 50 years old, accounting for 85.42%. The prescription amount was mostly between 301-500 yuan, accounting for 49.76%. Among the 300 selected patients with epigastric pain, the study group had significantly higher medication adherence and lower adverse reactions after medica-tion compared to the control group, with a statistically significant difference(P<0.05). Conclusion Chinese medicine formula granules have clear advantages in clinical applications, but their relatively high cost requires the exploration of further reasonable solutions to better promote the development of Chinese medicine formula granules.更多还原