【摘要】 目的 探究凝血功能和血小板各项参数对重症肝硬化患者的检测价值。方法 选择柳州市柳铁中心医院自2019年1月—2020年12月广西柳州市柳铁中心医院收治的80例重症肝硬化患者作为研究对象(设为研究组)，另同期80例非肝硬化患者作为参照对象(设为对照组)，两组研究对象均行凝血功能和血小板检测，对比两组研究对象凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)等凝血功能水平、血小板计数(PLT)、血小板压积(PCT)、平均血小板体积(MPV)、血小板分布宽度(PDW)等血小板参数水平、单用凝血功能、血小板各项参数及凝血功能联合血小板各项参数对重症肝硬化检测诊断的准确率。结果研究组患者TT、PT、APTT、MPV、PDW水平均显著高于对照组，研究组患者FIB、PLT、PCT水平均显著低于对照组，两组对比差异具有统计学意义(P<0.05)，且凝血功能联合血小板各项参数对重症肝硬化检测诊断的准确率显著高于单用凝血功能、血小板各项参数检测，组间对比差异具有统计学意义(P<0.05)。结论 凝血功能和血小板各项参数对重症肝硬化患者的检测价值显著，有利于患者病情的评估。更多还原

【Abstract】 Objective To explore the detection value of coagulation function and platelet parameters in patients with severe liver cirrhosis.Methods 80 patients with severe liver cirrhosis admitted to our hospital from January 2019 to December 2020 were selected as the research object(set as the study group),and 80 patients with non-cirrhosis who were hospitalized in Liuzhou Liutie Central Hospital during the same period were selected as the reference object(set For the control group),the two groups of subjects were tested for coagulation function and platelet,and the two groups of subjects were compared with thrombin time(TT),prothrombin time(PT), activated partial thromboplastin time(APTT),fibrinogen(FIB) and other levels of coagulation function,platelet count(PLT),platelet packed volume(PCT),mean platelet volume(MPV), platelet distribution width(PDW) and other platelet parameter levels, single-use coagulation function, platelet parameters and coagulation. The accuracy of function combined with platelet parameters for the detection and diagnosis of severe liver cirrhosis.Results The levels of TT, PT, APTT, MPV and PDW in the study group were significantly higher than those in the control group,and the levels of FIB,PLT and PCT in the study group were significantly lower than those in the control group.The comparison between the two groups was statistically significant,The comparison between groups was statistically significant(P<0.05).Conclusion The detection value of coagulation function and platelet parameters in patients with severe liver cirrhosis is significant,it is beneficial to the evaluation of patients’ condition.更多还原