【摘要】 骨质疏松是老年健康的极大威胁，其病理主要是骨密度降低，骨髓成骨细胞减少，破骨细胞骨吸收加剧，二者平衡打破，导致皮质骨胶原形成减少，松质骨丢失加快。自噬存在于所有真核生物的活动之中，对于骨重建平衡的维持起着重要作用。中医治疗骨质疏松前景良好，阴平阳秘是指阴阳平衡的一种状态，是中医整体观的体现。自噬在骨质疏松中体现着阴平阳秘，基于阴平阳秘探究药物干预骨质疏松中的细胞自噬，对中医药发展有重要价值。更多还原

【Abstract】 Osteoporosis is a great threat to the health of the elderly, is mainly due to a decrease in bone density, a reduction of osteoblasts in the bone marrow, and an increase in bone resorption by osteoclasts, with a disruption of the balance between the two, leading to a decrease in cortical collagen formation and accelerated cancellous bone loss.Autophagy is present in the activities of all eukaryotes and plays an important role in the maintenance of bone homeostasis.The treatment of TCM has a good prospect in osteoporosis, and Yin and Yang in equilibrium refers to a state of balance between yin and yang, which reflects the holistic view of TCM.Autophagy in osteoporosis is always a reflection of Yin and Yang in equilibrium, and the study of drug intervention in cellular autophagy in osteoporosis based on Yin and Yang in equilibrium has an important value for the development of TCM.更多还原